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Merck
CN

202789

Beryllium sulfate tetrahydrate

99.99% trace metals basis

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About This Item

Linear Formula:
BeSO4 · 4H2O
CAS Number:
7787-56-6
Molecular Weight:
177.14
NACRES:
NA.22
PubChem Substance ID:
24852118
UNSPSC Code:
12352302
EC Number:
236-842-2
MDL number:
MFCD00149156

Key Documents

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InChI key

DIMYTQPLZWDZFE-UHFFFAOYSA-L

InChI

1S/Be.H2O4S.4H2O/c;1-5(2,3)4;;;;/h;(H2,1,2,3,4);4*1H2/q+2;;;;;/p-2

SMILES string

[Be++].[H]O[H].[H]O[H].[H]O[H].[H]O[H].[O-]S([O-])(=O)=O

assay

99.99% trace metals basis

density

1.713 g/mL at 25 °C (lit.)

Application

Used in study of the dicarboxylate chelation of beryllium in an attempt to understand its physiological chemistry.

signalword

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Carc. 1B Inhalation - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 1 Inhalation - STOT SE 3

target_organs

Respiratory system, Skin,Respiratory Tract

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
MKCH6025
MKCG4241
MKCC1678
MKBP5108V
MKAA3609

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Michael Schmidt et al.
Inorganic chemistry, 36(10), 2040-2043 (1997-05-07)
Maleic and phthalic acids are found to react with Be(OH)(2), generated in situ from BeSO(4)(aq) and Ba(OH)(2)(aq), in aqueous solution at pH 3.0 or 4.4, respectively (25 degrees C), to give solutions containing the complexes (H(2)O)(2)Be[(OOCCH)(2)] (1) and (H(2)O)(2)Be[(OOC)(2)C(6)H(4)] (3).
P Victoratos et al.
Clinical and experimental immunology, 109(3), 569-578 (1997-10-27)
Antibody isotype affects biological activity of the antibodies and therefore should be considered in prevention of disease by vaccination. In previous reports, we demonstrated that adjuvants affect the antibody isotype switching process and favour the production of certain isotypes. The
Shannon Silva et al.
Journal of occupational and environmental hygiene, 6(12), 775-782 (2009-11-07)
Beryllium exposure in susceptible individuals leads to the development of chronic beryllium disease, a lung disorder marked by release of inflammatory cytokine and granuloma formation. We have previously reported that beryllium induces an immune response even in blood mononuclear cells
Fabiana Paladini et al.
Toxicological sciences : an official journal of the Society of Toxicology, 119(2), 257-269 (2010-10-27)
Occupational exposure to metals such as cobalt and beryllium represents a risk factor for respiratory health and can cause immune-mediated diseases. However, the way they act may be different. We show here that the two metals have a divergent effect
Priyatham Gorjala et al.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 23(6), 1061-1073 (2010-06-16)
In fibroblasts, beryllium salt causes activation of the p53 transcription factor and induction of a senescence-like state. It is not known whether Be(2+) can affect the proliferation of cancer cells, which are generally unsusceptible to senescence. A172 glioblastoma and RKO
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