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Merck
CN

205494

Dibutyltin dichloride

96%

Synonym(s):

Dibutyldichlorotin

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About This Item

Linear Formula:
(CH3CH2CH2CH2)2SnCl2
CAS Number:
683-18-1
Molecular Weight:
303.84
UNSPSC Code:
12352103
NACRES:
NA.22
PubChem Substance ID:
24852336
EC Number:
211-670-0
Beilstein/REAXYS Number:
3535484
MDL number:
MFCD00000518
Assay:
96%
Form:
solid

Key Documents

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InChI key

RJGHQTVXGKYATR-UHFFFAOYSA-L

InChI

1S/2C4H9.2ClH.Sn/c2*1-3-4-2;;;/h2*1,3-4H2,2H3;2*1H;/q;;;;+2/p-2

SMILES string

CCCC[Sn](Cl)(Cl)CCCC

assay

96%

form

solid

bp

135 °C/10 mmHg (lit.)

mp

37-40 °C (lit.)

Quality Level

100

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Related Categories

Application

  • Effects of dibutyltin compounds on PPARγ/RXRα activity: Studies the impact of various dibutyltin compounds, including dibutyltin dichloride, on adipogenesis and inflammation in mammalian cells, emphasizing their effects on the PPARγ/RXRα pathway (Milton et al., 2017).

signalword

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Muta. 2 - Repr. 1B - Skin Corr. 1B - Skin Sens. 1 - STOT RE 1 Oral - STOT SE 1 Oral

target_organs

thymus

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Regulatory Information

危险化学品
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Certificates of Analysis (COA)

Lot/Batch Number
SHBQ1704
SHBQ4379
SHBQ2566
MKCP3017
SHBJ2721

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Makoto Ema et al.
Environmental toxicology, 22(1), 44-52 (2007-02-14)
In this study, we examined the adverse effects of dibutyltin on initiation and maintenance of pregnancy after maternal administration during early pregnancy in mice. Following successful mating, female ICR mice were given dibutyltin dichloride (DBTCl) at 0, 7.6, 15.2, or
Fei Jiang et al.
Pancreas, 40(7), 1091-1096 (2011-09-20)
The α-tocopherol and tocotrienol-rich fraction (TRF) are considered effective antioxidants. This study aimed to compare the antioxidative and antifibrotic effects of α-tocopherol and TFR in dibutylin dichloride (DBTC)-induced chronic pancreatitis (CP) rats. Oral administration of α-tocopherol and TFR (both 800
H F Zhao et al.
Gut, 54(12), 1759-1767 (2005-11-15)
Monocyte chemoattractant protein 1 (MCP-1) is a member of the C-C chemokine family and exerts strong chemoattractant activity in monocytes, macrophages, and lymphocytes. Rat pancreatic fibrosis induced by dibutyltin dichloride (DBTC) is considered to be an appropriate chronic pancreatitis model
S Damrongsiri et al.
Journal of hazardous materials, 181(1-3), 1109-1114 (2010-06-29)
The harmful effects of organometallic compounds and their metabolites on the environment and human health require the development of more effective remediation methods. Surfactant enhanced remediation has been considered as a potential method for the removal of organometallic compounds; however
Brit Fitzner et al.
Digestive diseases and sciences, 54(2), 309-320 (2008-07-10)
Pancreatic stellate cells (PSC) play a key role in pancreatic fibrosis. Activation of PSC occurs in response to pro-fibrogenic stimuli and is maintained by autocrine loops of mediators, such as endothelin (ET)-1. Here, we have evaluated effects of the dual
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