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About This Item
Empirical Formula (Hill Notation):
C10H14N2O2
CAS Number:
Molecular Weight:
194.23
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
266-512-3
Beilstein/REAXYS Number:
1453764
MDL number:
Assay:
99%
Form:
solid
Quality Level
assay
99%
form
solid
mp
183-185 °C (lit.)
solubility
water: soluble 10 mg/mL, clear, colorless to faintly yellow
functional group
amine
SMILES string
CC(C)(C)\[N+]([O-])=C/c1cc[n+]([O-])cc1
InChI
1S/C10H14N2O2/c1-10(2,3)12(14)8-9-4-6-11(13)7-5-9/h4-8H,1-3H3/b12-8+
InChI key
RNRMWTCECDHNQU-XYOKQWHBSA-N
Application
α-(4-Pyridyl N-oxide)-N-tert-butylnitrone was used as spin trapping agent to detect:
- the formation of hydroxyl radical adducts during decomposition of hydrogen peroxide in the presence of nickel (II) oligopeptides
- hydroxyl radicals and selenide radical anions
Spin trap reagent used to measure ethanol oxidation to 1-hydroxyethyl radical (HER) which can bind to protein. Has also been used in studies of DNA methylation, iron-mediated polyunsaturated fatty acid peroxidation, and free-radical formation by Alzheimer β-amyloid peptide. The formation of hydroxyl radical in chondrocytes and cartilage has been detected using POBN.
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Bulletin of the Chemical Society of Japan, 64, 1976-1976 (1991)
Measurement of hydroxyl radical activity in a soil slurry using the spin trap a-(4-pyridyl-1-oxide)-N-tert-butylnitrone.
Huling SG, et al.
Environmental Science & Technology, 32(21), 3436-3441 (1998)
J. Photochem. Photobiol., A, 56, 89-89 (1991)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 215430-1G | 04061838773739 |