217808
cis-Aconitic anhydride
95%
Synonym(s):
cis-Propene-1,2,3-tricarboxylic anhydride
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About This Item
Empirical Formula (Hill Notation):
C6H4O5
CAS Number:
Molecular Weight:
156.09
UNSPSC Code:
12162002
NACRES:
NA.23
PubChem Substance ID:
EC Number:
228-663-3
Beilstein/REAXYS Number:
127575
MDL number:
InChI key
GVJRTUUUJYMTNQ-UHFFFAOYSA-N
InChI
1S/C6H4O5/c7-4(8)1-3-2-5(9)11-6(3)10/h2H,1H2,(H,7,8)
SMILES string
OC(=O)CC1=CC(=O)OC1=O
assay
95%
mp
75-78 °C (lit.)
Quality Level
Related Categories
signalword
Danger
hcodes
Hazard Classifications
Skin Corr. 1B
Storage Class
8A - Combustible corrosive hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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A V Martynov et al.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 25(7), 414-417 (2005-07-19)
The antiproliferative activity of aconitylated (AIFN) and succinylated (SIFN) derivatives of recombinant interferon- alpha2b (IFN-alpha2b) was examined. Acylation of IFN-alpha2b was performed by succinic and cis-aconitic anhydrides. Antiproliferative properties of AIFN and SIFN were studied in vitro on the CaOv
Xiangxuan Huang et al.
Materials science & engineering. C, Materials for biological applications, 90, 27-37 (2018-06-02)
The development of intelligent drug delivery system that can efficiently deliver doxorubicin (DOX) to tumor site with controlled drug release performance and enhanced therapeutic efficacy is of great significance for cancer chemotherapy. In this report, a nano-prodrug system was prepared
K L Law et al.
Anticancer research, 10(3), 845-852 (1990-05-01)
Antibody-drug conjugates containing a linkage susceptible to lysosomal hydrolases were constructed by coupling peptide-daunorubicin (DNR) derivatives to MAb. Using a modification in the method of Trouet et al, peptide derivatives of DNR containing the sequences Ala-Leu and Ala-Leu-Ala-Leu linked to
Huijuan Song et al.
Colloids and surfaces. B, Biointerfaces, 136, 365-374 (2015-10-05)
Self-assembled prodrug nanoparticles have demonstrated great promise in cancer chemotherapy. In the present study, we developed a new kind of prodrug nanoparticles for targeted drug delivery. PEGylated doxorubicin conjugate with an acid-cleavable cis-aconityl spacer was prepared. Then it was functionalized
Jinbiao Gao et al.
Colloids and surfaces. B, Biointerfaces, 174, 416-425 (2018-11-28)
Ultrasound-triggered delivery system is among the various multifunctional and stimuli-responsive strategies that hold great potential as a robust solution to the challenges of localized drug delivery and gene therapy. In this work, we developed an ultrasound-triggered delivery system PFP/C9F17-PAsp(DET)/CAD/PGA-g-mPEG nanodroplet
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