219746
DL-Homocysteic acid
97%
Synonym(s):
DL-2-Amino-4-sulfobutyric acid
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About This Item
Linear Formula:
HO3SCH2CH2CH(NH2)CO2H
CAS Number:
Molecular Weight:
183.18
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
207-991-0
MDL number:
Assay:
97%
Form:
solid
InChI key
VBOQYPQEPHKASR-UHFFFAOYSA-N
InChI
1S/C4H9NO5S/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H,8,9,10)
SMILES string
NC(CCS(O)(=O)=O)C(O)=O
assay
97%
form
solid
mp
273 °C (dec.) (lit.)
solubility
water: soluble 50 mg/mL, clear to slightly hazy, colorless to yellow
functional group
amine, carboxylic acid, sulfonic acid
General description
Complexes of DL-homocysteic acid with Na+, Cu2+, Zn2+ and Ni2+ has been synthesized. DL-Homocysteic acid induces oxidative stress in brain of immature rats.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Jaroslava Folbergrová et al.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 31(2), 123-130 (2012-12-15)
We have recently demonstrated the evidence of oxidative stress in brain of immature rats during seizures induced by DL-homocysteic acid (DL-HCA). The aim of the present study was to investigate the antioxidant defense mechanisms under these conditions. Seizures were induced
Hui-Zhen Jia et al.
Guang pu xue yu guang pu fen xi = Guang pu, 27(7), 1291-1294 (2007-10-20)
The complexes of DL-homocysteic acid (DLH) with Na+, Cu2+, Zn2+ and Ni2+ were synthesized and elemental analyses were used to detect the compositions of these complexes. FTIR spectroscopy was employed to study these coordination structures. The results indicated that all
Tohru Hasegawa et al.
PloS one, 5(1), e8593-e8593 (2010-01-26)
Alzheimer's disease (AD) is an age-associated progressive neurodegenerative disorder with dementia, the exact pathogenic mechanisms of which remain unknown. We previously reported that homocysteic acid (HA) may be one of the pathological biomarkers in the brain with AD and that
Ali Moazzami et al.
Journal of applied physiology (Bethesda, Md. : 1985), 108(5), 1336-1346 (2010-02-06)
We have demonstrated that stimulation of somatic afferents during electroacupuncture (EA) inhibits sympathoexcitatory cardiovascular rostral ventrolateral medulla (rVLM) neurons and reflex responses. Furthermore, EA at P5-P6 acupoints over the median nerve on the forelimb activate serotonin (5-HT)-containing neurons in the
Asya Makhro et al.
American journal of physiology. Cell physiology, 298(6), C1315-C1325 (2010-05-12)
N-methyl-d-aspartate (NMDA) receptors are ligand-gated nonselective cation channels mediating fast neuronal transmission and long-term potentiation in the central nervous system. These channels have a 10-fold higher permeability for Ca(2+) compared with Na(+) or K(+) and binding of the agonists (glutamate
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