Skip to Content
Merck
CN

Key Documents

View All Documentation

22490

Chelidamic acid hydrate

≥97.0% (dried material, T), ~1 mol/mol water

Synonym(s):

1,4-Dihydro-4-oxo-2,6-pyridinedicarboxylic acid hydrate, 4-Hydroxypyridine-2,6-dicarboxylic acid

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):
C7H5NO5 · xH2O
CAS Number:
138-60-3
Molecular Weight:
183.12 (anhydrous basis)
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
57647988
EC Number:
205-335-8
Beilstein/REAXYS Number:
476229
MDL number:
MFCD03818117
Assay:
≥97.0% (dried material, T)
Form:
powder
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Quality Level

200

assay

≥97.0% (dried material, T)

form

powder

impurities

~1 mol/mol water

mp

267 °C (dec.) (lit.)

functional group

carboxylic acid

SMILES string

O.OC(=O)C1=CC(=O)C=C(N1)C(O)=O

InChI

1S/C7H5NO5.H2O/c9-3-1-4(6(10)11)8-5(2-3)7(12)13;/h1-2H,(H,8,9)(H,10,11)(H,12,13);1H2

InChI key

SNGPHFVJWBKEDG-UHFFFAOYSA-N

Application

Chelidamic acid hydrate was used in the synthesis of 4-Chloro-N,N,N′,N′-tetraethylpyridine-2,6-dicarboxamide.

Biochem/physiol Actions

Among the most potent of the tested "conformationally restricted glutamate analogs" as an inhibitor of glutamate decarboxylase.

Still not finding the right product?

Explore all of our products under Chelidamic acid hydrate

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCN8455
BCCG4193
BCCF0445
BCCD8768
BCCD2183

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Anne-Sophie Chauvin et al.
Organic & biomolecular chemistry, 1(4), 737-740 (2003-08-22)
The synthesis of 4-substituted dipicolinic acid derivatives requiring palladium catalysis is described. A keto-enol equilibrium has been observed, depending on the nature of the 2,6-position substituents.
[Antiviral activity of chelidamic acid derivatives].
V E Iavorovskaia et al.
Voprosy virusologii, 29(3), 361-363 (1984-05-01)
Maya Tutughamiarso et al.
Acta crystallographica. Section C, Crystal structure communications, 68(Pt 9), o344-o350 (2012-09-01)
Different tautomeric and zwitterionic forms of chelidamic acid (4-hydroxypyridine-2,6-dicarboxylic acid) are present in the crystal structures of chelidamic acid methanol monosolvate, C(7)H(5)NO(5)·CH(4)O, (Ia), dimethylammonium chelidamate (dimethylammonium 6-carboxy-4-hydroxypyridine-2-carboxylate), C(2)H(8)N(+)·C(7)H(4)NO(5)(-), (Ib), and chelidamic acid dimethyl sulfoxide monosolvate, C(7)H(5)NO(5)·C(2)H(6)OS, (Ic). While the zwitterionic
View All Related Papers

Global Trade Item Number

SKUGTIN
22490-25G-F04061838779304