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Merck
CN

233277

2,6-Difluoropyridine

99%

Synonym(s):

2,6-Difluoropyridine

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About This Item

Empirical Formula (Hill Notation):
C5H3F2N
CAS Number:
Molecular Weight:
115.08
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
216-152-8
Beilstein/REAXYS Number:
1422549
MDL number:
Assay:
99%
Form:
liquid
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Quality Segment

assay

99%

form

liquid

refractive index

n20/D 1.437 (lit.)

bp

124.5 °C/743 mmHg (lit.)

density

1.268 g/mL at 25 °C (lit.)

functional group

fluoro

SMILES string

Fc1cccc(F)n1

InChI

1S/C5H3F2N/c6-4-2-1-3-5(7)8-4/h1-3H

InChI key

MBTGBRYMJKYYOE-UHFFFAOYSA-N

General description

Lithium diisopropylamide (LDA)-mediated ortholithiations of 2,6-difluoropyridine in tetrahydrofuran at -78°C has been studied using a combination of IR and NMR spectroscopic and computational methods. Polycondensation of bistrimethylsilyl derivatives of various diphenols with 2,6-difluoropyridine in N-methylpyrrolidone in the presence of K2CO3 has been investigated.

Application

2,6-Difluoropyridine has been used in the preparation of poly(pyridine ether)s via polycondensation with silylated 1,1,1-tris(4-hydroxyphenyl)ethane.


Pictograms

FlameExclamation mark

Signal Word

Warning

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class

3 - Flammable liquids

WGK

WGK 3

Flash Point (°F)

91.4 °F - closed cup

Flash Point (°C)

33 °C - closed cup

PPE (personal protective equipment)

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter



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