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Merck
CN

236357

3-Hydroxypropionitrile

ReagentPlus®, 99%

Synonym(s):

2-Cyanoethanol, Ethylene cyanohydrin, Hydracrylonitrile

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About This Item

Linear Formula:
HOCH2CH2CN
CAS Number:
Molecular Weight:
71.08
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
635773
Assay:
99%
Form:
liquid
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vapor density

2.5 (vs air)

Quality Level

vapor pressure

<0.1 mmHg ( 20 °C)

product line

ReagentPlus®

assay

99%

form

liquid

autoignition temp.

922 °F

expl. lim.

12.1 %

refractive index

n20/D 1.425 (lit.)

bp

228 °C (lit.)

mp

−46 °C (lit.)

solubility

diethyl ether: slightly soluble 2.3 % (w/w) at 15 °C(lit.), acetone: miscible(lit.), benzene: insoluble(lit.), carbon disulfide: insoluble(lit.), carbon tetrachloride: insoluble(lit.), ethanol: miscible(lit.), petroleum ether: insoluble(lit.), water: miscible(lit.)

density

1.04 g/mL at 25 °C (lit.)

functional group

hydroxyl, nitrile

storage temp.

2-8°C

SMILES string

OCCC#N

InChI

1S/C3H5NO/c4-2-1-3-5/h5H,1,3H2

InChI key

WSGYTJNNHPZFKR-UHFFFAOYSA-N

Application

3-Hydroxypropionitrile has been used:
  • as polar solvent to investigate the orientation of the phospholipid at the surface of the polar solvents by neutral impact collision ion scattering spectroscopy
  • in solid state composite electrolyte for dye-sensitized solar cells
  • as a reagent for carboxyl protection in peptide synthesis

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany


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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter



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Hongxia Wang et al.
The journal of physical chemistry. B, 110(12), 5970-5974 (2006-03-24)
It was observed that the ionic conductivity of the solid-state electrolyte LiI/3-hydroxypropionitrile (HPN) = 1:4 (molar ratio) decreased dramatically with increasing iodine (I(2)) concentration, which differs from the conduction behavior of the Grotthuss transport mechanism observed in liquid or gel
3-hydroxypropionitrile: A new reagent for carboxyl protection in peptide synthesis.
Misra PK, et al.
Tetrahedron Letters, 30(27), 3569-3572 (1989)
Hartwig Pohl et al.
Langmuir : the ACS journal of surfaces and colloids, 26(4), 2473-2476 (2009-11-20)
Phospholipids are a main component of cell membranes. Therefore, the experimental investigation of the self-organization of phospholipids is of great interest. Here we present results concerning the orientation of the phospholipid 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) at the surface of the polar solvents



Global Trade Item Number

SKUGTIN
T6025-1L04061837348693
T9650-4L04061838260482
T8280-1L04061835519149
T9650-1L04061838260475
T4038-5X1L04061838260222
T4038-1L04061838116208
236357-50G04061836825942