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About This Item
Linear Formula:
C6H5SO2CH=CH2
CAS Number:
Molecular Weight:
168.21
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
226-890-2
Beilstein/REAXYS Number:
1906894
MDL number:
Assay:
99%
Form:
solid
InChI key
UJTPZISIAWDGFF-UHFFFAOYSA-N
InChI
1S/C8H8O2S/c1-2-11(9,10)8-6-4-3-5-7-8/h2-7H,1H2
SMILES string
C=CS(=O)(=O)c1ccccc1
assay
99%
form
solid
mp
67-69 °C (lit.)
solubility
organic solvents: soluble(lit.)
functional group
sulfone
Quality Level
Gene Information
human ... LOC129293(129293)
Related Categories
General description
Phenyl vinyl sulfone, a synthetic inhibitor of cysteine protease, exhibits antihelminthic and antiprotozoal properties.
Application
Phenyl vinyl sulfone was used as a common reagent in a variety of cycloaddition reactions to form cyclopropanes, cyclohexenes and cyclooctadienes.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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Tetrahedron Letters, 34, 7583-7583 (1993)
Aldrichimica Acta, 15, 34-34 (1982)
Tetrahedron, 49, 5495-5495 (1993)
Eric T Larson et al.
The Journal of biological chemistry, 284(39), 26839-26850 (2009-07-15)
The protozoan parasite Toxoplasma gondii relies on post-translational modification, including proteolysis, of proteins required for recognition and invasion of host cells. We have characterized the T. gondii cysteine protease cathepsin L (TgCPL), one of five cathepsins found in the T.
M Varenberg et al.
Journal of the Royal Society, Interface, 5(24), 785-789 (2007-10-18)
To analyse the performance of mushroom-shaped fibrillar adhesive microstructure, its behaviour was studied during different stages of attachment-loading-detachment cycle. Visualizing the evolutions of real contact area of single microfibres, it is shown that the mushroom-shaped geometry of contact elements promotes
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