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Merck
CN

254819

Hydroquinidine hydrochloride

98%

Synonym(s):

Dihydroquinidine hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C20H26N2O2 · HCl
CAS Number:
Molecular Weight:
362.89
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352005
EC Number:
216-024-1
MDL number:
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InChI key

MULXTQKDWYBJMO-VJAUXQICSA-N

InChI

1S/C20H26N2O2.ClH/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;/h4-6,8,11,13-14,19-20,23H,3,7,9-10,12H2,1-2H3;1H/t13-,14-,19+,20-;/m0./s1

SMILES string

Cl.CC[C@H]1CN2CC[C@H]1C[C@@H]2[C@@H](O)c3ccnc4ccc(OC)cc34

assay

98%

form

powder

optical activity

[α]20/D +185.2°, c = 1.3 in H2O

mp

277-279 °C (lit.)

functional group

hydroxyl

Quality Level

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Regulatory Information

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Fiorenzo Gaita et al.
Journal of the American College of Cardiology, 43(8), 1494-1499 (2004-04-20)
The purpose of this study was to evaluate the efficacy of various antiarrhythmic drugs at prolonging the QT interval into the normal range and preventing ventricular arrhythmias in patients with short QT syndrome. Short QT syndrome is a recently described
Saleem Aladaileh et al.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 148(4), 470-480 (2007-10-24)
Phenoloxidase (PO) activity was studied in Sydney rock oysters (Saccostrea glomerata). As in other molluscs, PO was found to exist as a pro-enzyme (proPO) in hemocytes. ProPO could be activated to PO by exogenous proteases (trypsin and chymotrypsin), exposure of
Ad Kane et al.
Annales de cardiologie et d'angeiologie, 61(4), 292-295 (2011-06-15)
A 45-year-old man was hospitalized for syncope due to fascicular ventricular tachycardia degenerating into ventricular fibrillation (VF). The electrocardiogram showed an early repolarization syndrome. The arrhythmia was repetitive and disappeared after oral hydroquinidine. An implantable cardioverter-defibrillator (ICD) was implanted; subsequently
Arti T Navare et al.
Journal of mass spectrometry : JMS, 45(6), 635-642 (2010-06-09)
Atmospheric pressure (AP) matrix-assisted laser desorption/ionization (MALDI) is known to suffer from poor ion transfer efficiencies as compared to conventional vacuum MALDI (vMALDI). To mitigate these issues, a new AP-MALDI ion source utilizing a coaxial gas flow was developed. Nitrogen
C K Mannesse et al.
Nederlands tijdschrift voor geneeskunde, 147(13), 585-587 (2003-04-19)
Two women, aged 77 and 73 years, and one man, aged 71 years, were admitted because of a serious adverse drug reaction (ADR). The first woman had a probable adverse drug reaction caused by digoxin after the addition of a

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