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260428

3-Ethoxy-1,2-propanediol

98%

Synonym(s):

3-Ethoxypropane-1,2-diol, Glycerol 1-ethyl ether

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About This Item

Linear Formula:
C2H5OCH2CH(OH)CH2OH
CAS Number:
1874-62-0
Molecular Weight:
120.15
NACRES:
NA.23
PubChem Substance ID:
24855753
UNSPSC Code:
12162002
EC Number:
217-503-8
MDL number:
MFCD00009989
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Quality Segment

100

assay

98%

form

liquid

refractive index

n20/D 1.441 (lit.)

bp

222 °C (lit.)

density

1.063 g/mL at 25 °C (lit.)

SMILES string

CCOCC(O)CO

InChI

1S/C5H12O3/c1-2-8-4-5(7)3-6/h5-7H,2-4H2,1H3

InChI key

LOSWWGJGSSQDKH-UHFFFAOYSA-N

General description

3-Ethoxy-1,2-propanediol (also known as glycerol α-ethyl ether) is primarily used as a solvent in various industries, including pharmaceuticals, cosmetics, and coatings. It can also be used as a substrate in the synthesis of cyclic phosphates for use in flame retardants.

Application

3-Ethoxy-1,2-propanediol (EGE) can be used as a crosslinking agent in the development of poly(glycidol) hydrogels for use in various biomedical applications such as tissue engineering and drug delivery. It is also used as a potential component in a bio-based solvent system for dissolving or processing nitrocellulose.

3-Ethoxy-1,2-propanediol can be used as:

  • An analyte protector in gas chromatographic analysis of pesticides.
  • An acceptor substrate in glycosylation reaction by sucrose phosphorylase.
It can also be used as a precursor in the Mitsunobu reaction of N-hydroxy phthalimide with poly(glycidol) and synthesis of 2-(3-ethoxy-2-hydroxypropoxy) isoindoline-1,3-dione.

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pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H315

Hazard Classifications

Skin Irrit. 2

Storage Class

10 - Combustible liquids

wgk

WGK 2

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

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