270369
1,1,2-Trichlorotrifluoroethane
HPLC grade, ≥99.9%
Synonym(s):
1,1,2-Trichloro-1,2,2-trifluoroethane, 1,1,2-Trichloro-trifluoroethane, Genetron® 113
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About This Item
Linear Formula:
ClCF2CCl2F
CAS Number:
Molecular Weight:
187.38
EC Number:
200-936-1
UNSPSC Code:
12190000
PubChem Substance ID:
Beilstein/REAXYS Number:
1740335
MDL number:
grade
HPLC grade
vapor density
6.5 (vs air)
vapor pressure
5.5 psi ( 20 °C)
assay
≥99.9%
form
liquid
autoignition temp.
1256 °F
technique(s)
HPLC: suitable
impurities
<0.010% water
evapn. residue
<0.0005%
refractive index
n20/D 1.358 (lit.)
bp
47-48 °C (lit.)
mp
−35 °C (lit.)
density
1.57 g/mL at 25 °C (lit.)
λ
H2O reference
UV absorption
λ: 231 nm Amax: 1.00, λ: 240 nm Amax: 0.20, λ: 260-400 nm Amax: 0.01
SMILES string
FC(F)(Cl)C(F)(Cl)Cl
InChI
1S/C2Cl3F3/c3-1(4,6)2(5,7)8
InChI key
AJDIZQLSFPQPEY-UHFFFAOYSA-N
Packaging
Packaged under nitrogen, bottles are Sealed for Quality™
Legal Information
Genetron is a registered trademark of Honeywell International Inc.
signalword
Warning
hcodes
Hazard Classifications
Aquatic Chronic 2 - Eye Irrit. 2 - Ozone 1
Storage Class
10 - Combustible liquids
wgk
WGK 2
flash_point_f
383.0 °F
flash_point_c
195 °C
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
Regulatory Information
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Wei Chen et al.
Autophagy, 10(7), 1272-1284 (2014-06-07)
Ribonucleotide reductase (RNR) plays a critical role in catalyzing the biosynthesis and maintaining the intracellular concentration of 4 deoxyribonucleoside triphosphates (dNTPs). Unbalanced or deficient dNTP pools cause serious genotoxic consequences. Autophagy is the process by which cytoplasmic constituents are degraded
Yun-Ru Chen et al.
Oncotarget, 7(2), 1984-1999 (2015-12-18)
Macroautophagy can promote cellular survival or death depending on the cellular context and its extent. We hypothesized that autophagy induction would synergize with a therapeutic agent targeting the autophagic cargo. To test this hypothesis, we treated breast cancer MDA-MB-231 cells
H K Xiao et al.
American Industrial Hygiene Association journal, 51(7), 402-404 (1990-07-01)
Results obtained using Fourier transform infrared spectrophotometry (FTIR) for the analysis of samples of carbon disulfide (CS2) eluates containing trichloroethylene (TCE) and Freon from charcoal air sampling tubes were evaluated by comparison with results obtained when using gas chromatography (GC).