Key Documents

View All Documentation

279072

Cyproheptadine hydrochloride sesquihydrate

Name: Cyproheptadine hydrochloride sesquihydrate
Brand: ALDRICH

99%

Synonym(s):

4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-methyl-piperidine hydrochloride hydrate

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):

C₂₁H₂₁N · HCl · 1.5H₂O

CAS Number:

41354-29-4

Molecular Weight:

350.88

PubChem Substance ID:

24856848

UNSPSC Code:

12352100

NACRES:

NA.22

EC Number:

213-535-1

Assay:

99%

Form:

solid

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Quality Level

100

assay

99%

form

solid

mp

165 °C (dec.) (lit.)

solubility

1 M NH4OH: soluble 25 mg/mL, clear, colorless to faintly yellow

SMILES string

O.O.O.Cl.CN1CCC(\CC1)=C2\c3ccccc3C=Cc4ccccc24.CN5CCC(\CC5)=C6\c7ccccc7C=Cc8ccccc68

InChI

1S/2C21H21N.ClH.3H2O/c2*1-22-14-12-18(13-15-22)21-19-8-4-2-6-16(19)10-11-17-7-3-5-9-20(17)21;;;;/h2*2-11H,12-15H2,1H3;1H;3*1H2

InChI key

PXCSXCDWTUPVIM-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Chemical Building Blocks

Heterocyclic Building Blocks

Chemistry & Biochemicals

General description

Cyproheptadine hydrochloride sesquihydrate is an antihistamine and is an antagonist of serotonin and histamine. It induced preventive effect against the development of pergolide-induced valvulopathy in a rat model.

pictograms

GHS07

signalword

Warning

hcodes

H302,H315,H319,H335

pcodes

P261 - P264 - P271 - P301 + P312 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

The structure of an antihistamine: cyproheptadine hydrochloride sesquihydrate.

Birknes BJORN.

Acta Crystallographica Section B, Structural Science, 33(3), 687-691 (1977)

Cyproheptadine prevents pergolide-induced valvulopathy in rats: an echocardiographic and histopathological study.

Steven Droogmans et al.

American journal of physiology. Heart and circulatory physiology, 296(6), H1940-H1948 (2009-04-07)

Serotonergic drugs, such as pergolide, have been associated with the development of cardiac valvular myxoid thickening and regurgitation in humans and more recently in rats. These effects are potentially mediated by the 5-hydroxytryptamine (5-HT)(2B) receptor (5-HT(2B)R). Therefore, we sought to

Development and validation of an ultra-performance liquid chromatography method for simultaneous analysis of 20 antihistaminics in dietary supplements.

Jung Yeon Kim et al.

Biomedical chromatography : BMC, 29(3), 465-474 (2014-08-01)

The purpose of this study was to develop and validate an ultra-performance liquid chromatography method for simultaneous analysis of 20 antihistamines (illegal additives) in dietary supplements. The limits of detection and quantitation of the method ranged from 1.5 to 2.5

Global Trade Item Number

SKU	GTIN
279072-5G	04061826211274

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service