280216
Nα-Acetylglycinamide
97%
Synonym(s):
2-Acetamidoacetamide
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About This Item
Linear Formula:
CH3CONHCH2CONH2
CAS Number:
Molecular Weight:
116.12
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
220-058-2
MDL number:
Assay:
97%
InChI key
WQELDIQOHGAHEM-UHFFFAOYSA-N
InChI
1S/C4H8N2O2/c1-3(7)6-2-4(5)8/h2H2,1H3,(H2,5,8)(H,6,7)
SMILES string
CC(=O)NCC(N)=O
assay
97%
mp
140-143 °C (lit.)
Application
Nα-Acetylglycinamide (2-Acetamidoacetamide) was used in the preparation of 3-unsubstituted 2-pyridones by a tandem reaction with chalcones.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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[The systems analysis of the effect of piracetam, glycine and N-acetylglycinamide on long-term learning].
A I Machula et al.
Eksperimental'naia i klinicheskaia farmakologiia, 56(4), 55-57 (1993-07-01)
Tomohisa Nezu et al.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 32(5), 844-850 (2012-01-19)
Limited evidence exists on the relationships between severity of white-matter lesions (WMLs) and cerebral hemodynamics in patients without major cerebral artery disease. To examine changes of cerebral blood flow (CBF), oxygen metabolism, and vascular reserve capacity associated with severity of
V I Naumova et al.
Biulleten' eksperimental'noi biologii i meditsiny, 107(6), 711-713 (1989-06-01)
The effect of electroshock (ECS) and piracetam, oxiracetam or N-acetylglycinamide on the passive avoidance conditioned response in rats was studied. The antiemetic effect of the compounds was examined in cats as well. The results obtained allowed us to distinct the
Matthew Auton et al.
Biochemistry, 43(5), 1329-1342 (2004-02-06)
With knowledge of individual transfer free energies of chemical groups that become newly exposed on protein denaturation and assuming the group transfer free energy contributions are additive, it should be possible to predict the stability of a protein in the
A Regioselective Tandem Reaction between Chalcones and 2-Acetamidoacetamide Promoted by Cs2 CO3 for the Preparation of 3-Unsubstituted 2-Pyridones.
Wang S, et al.
Synthesis, 2003(04), 0487-0490 (2003)
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