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Merck
CN

281255

1,4-Dihydroxy-2-naphthoic acid

97%

Synonym(s):

1,4-Dihydroxy-2-carboxy naphthoic acid, 1,4-Dihydroxy-2-naphthalenecarboxylic acid, 1,4-Dihydroxy-2-naphthoate

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About This Item

Linear Formula:
(HO)2C10H5CO2H
CAS Number:
Molecular Weight:
204.18
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
250-674-7
MDL number:
Assay:
97%
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Quality Level

assay

97%

mp

220 °C (dec.) (lit.)

functional group

carboxylic acid

SMILES string

OC(=O)c1cc(O)c2ccccc2c1O

InChI

1S/C11H8O4/c12-9-5-8(11(14)15)10(13)7-4-2-1-3-6(7)9/h1-5,12-13H,(H,14,15)

InChI key

VOJUXHHACRXLTD-UHFFFAOYSA-N

General description

1,4-Dihydroxy-2-naphthoic acid from Propionibacterium freudenreichii is known to promote the proliferation of Bifidobacterium. It has potential therapeutic application for psoriasis treatment.


pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Site of prenylation reaction in synthesis of phylloquinone (vitamin K1) by spinach chloroplasts.
G Schultz et al.
European journal of biochemistry, 117(2), 329-332 (1981-07-01)
Pallavi P Murugkar et al.
Journal of oral microbiology, 12(1), 1814666-1814666 (2020-11-20)
The vast majority of bacteria on earth have not yet been cultivated. There are many bacterial phyla with no cultivated examples including most members of the Candidate Phylum Radiation with the exception of human oral isolates from the phylum Saccharibacteria.
Biosynthesis of vitamin K (menaquinone) in bacteria.
R Bentley et al.
Microbiological reviews, 46(3), 241-280 (1982-09-01)



Global Trade Item Number

SKUGTIN
281255-25G04061826219720