282693
(S)-(+)-2-Phenylglycinol
98%, for peptide synthesis
Synonym(s):
(S)-2-Amino-2-phenylethanol, L-(+)-α-Phenylglycinol
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About This Item
Linear Formula:
C6H5CH(NH2)CH2OH
CAS Number:
Molecular Weight:
137.18
Beilstein:
3196190
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.22
Product Name
(S)-(+)-2-Phenylglycinol, 98%
Assay
98%
form
solid
optical activity
[α]19/D +33°, c = 0.75 in 1 M HCl
optical purity
ee: 99% (GLC)
reaction suitability
reaction type: solution phase peptide synthesis
mp
75-78 °C (lit.)
application(s)
peptide synthesis
SMILES string
N[C@H](CO)c1ccccc1
InChI
1S/C8H11NO/c9-8(6-10)7-4-2-1-3-5-7/h1-5,8,10H,6,9H2/t8-/m1/s1
InChI key
IJXJGQCXFSSHNL-MRVPVSSYSA-N
Application
Used in a synthesis of chiral, unsymmetrical bisoxazolines.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Tetrahedron Asymmetry, 17, 2270-2270 (2006)
Jin Han et al.
European journal of medicinal chemistry, 124, 583-607 (2016-09-12)
The present study describes our continuous effort to develop epidermal growth factor receptor (EGFR) inhibitors based on the 6-aryl-pyrrolo[2,3-d]pyrimidin-4-amine scaffold. The activity-ADME space has been evaluated by synthesizing 43 new structures, including four variations of the 4-amino group and 34
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