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Merck
CN

283150

2,4,6-Trimethylpyridinium p-toluenesulfonate

98%

Synonym(s):

p-Toluenesulfonic acid sym-Collidine salt, sym-Collidinium p-toluenesulfonate, CTPS

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About This Item

Empirical Formula (Hill Notation):
C15H19NO3S
CAS Number:
Molecular Weight:
293.38
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
98%
Form:
solid
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assay

98%

form

solid

mp

128-130 °C (lit.)

functional group

tosylate

SMILES string

Cc1cc(C)nc(C)c1.Cc2ccc(cc2)S(O)(=O)=O

InChI

1S/C8H11N.C7H8O3S/c1-6-4-7(2)9-8(3)5-6;1-6-2-4-7(5-3-6)11(8,9)10/h4-5H,1-3H3;2-5H,1H3,(H,8,9,10)

InChI key

VEXWNPGPVMYVDU-UHFFFAOYSA-N

Application

2,4,6-Trimethylpyridinium p-toluenesulfonate may be used in chemical synthesis.


pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Bo Zhang et al.
Journal of genetics and genomics = Yi chuan xue bao, 47(3), 131-143 (2020-04-23)
Compartmentation of enzymes via filamentation has arisen as a mechanism for the regulation of metabolism. In 2010, three groups independently reported that CTP synthase (CTPS) can assemble into a filamentous structure termed the cytoophidium. In searching for CTPS-interacting proteins, here
Eric M Lynch et al.
Nature structural & molecular biology, 27(1), 42-48 (2019-12-25)
Many enzymes assemble into defined oligomers, providing a mechanism for cooperatively regulating activity. Recent studies have described a mode of regulation in which enzyme activity is modulated by polymerization into large-scale filaments. Here we describe an ultrasensitive form of polymerization-based
Zhe Sun et al.
Journal of genetics and genomics = Yi chuan xue bao, 46(2), 65-74 (2019-03-13)
CTP synthase (CTPS), the rate-limiting enzyme in de novo CTP biosynthesis, has been demonstrated to assemble into evolutionarily conserved filamentous structures, termed cytoophidia, in Drosophila, bacteria, yeast and mammalian cells. However, the regulation and function of the cytoophidium remain elusive.



Global Trade Item Number

SKUGTIN
283150-5G04061832541020