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283320

Butyl lactate

Name: Butyl lactate
Brand: ALDRICH

98%

Synonym(s):

α-Hydroxypropionic acid butyl ester, (±)-n-Butyl lactate, 2-Hydroxypropanoic acid butyl ester, Butyl α-hydroxypropionate, Butyl 2-hydroxypropanoate, n-Butyl lactate

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About This Item

Linear Formula:

CH₃CH(OH)CO₂(CH₂)₃CH₃

CAS Number:

138-22-7

Molecular Weight:

146.18

NACRES:

NA.22

PubChem Substance ID:

24857101

UNSPSC Code:

12352100

EC Number:

205-316-4

MDL number:

MFCD00004519

Assay:

98%

Form:

liquid

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Properties

vapor density

5.04 (vs air)

Quality Level

200

vapor pressure

0.4 mmHg ( 20 °C)

assay

98%

form

liquid

refractive index

n20/D 1.421 (lit.)

bp

185-187 °C (lit.)

mp

−28 °C (lit.)

density

0.984 g/mL at 25 °C (lit.)

functional group

ester, hydroxyl

SMILES string

CCCCOC(=O)C(C)O

InChI

1S/C7H14O3/c1-3-4-5-10-7(9)6(2)8/h6,8H,3-5H2,1-2H3

InChI key

MRABAEUHTLLEML-UHFFFAOYSA-N

Description

Application

Butyl lactate has been used:

in the preparation of solid lipid nanoparticles by a solvent emulsification–diffusion technique
in the synthesis of nanoparticles of griseofulvin from water dilutable microemulsions by the solvent diffusion technique
as cosurfactant on the preparation of microemulsions with anionic surfactant

Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

156.2 °F - closed cup

flash_point_c

69 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

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Preparation of solid lipid nanoparticles by a solvent emulsification-diffusion technique.

Michele Trotta et al.

International journal of pharmaceutics, 257(1-2), 153-160 (2003-04-25)

A preparation method for nanoparticles based on the emulsification of a butyl lactate or benzyl alcohol solution of a solid lipid in an aqueous solution of different emulsifiers, followed by dilution of the emulsion with water, was used to prepare

Preparation of griseofulvin nanoparticles from water-dilutable microemulsions.

Michele Trotta et al.

International journal of pharmaceutics, 254(2), 235-242 (2003-03-08)

Nanoparticles of griseofulvin, a model drug with poor solubility and low bioavailability, were prepared from water dilutable microemulsions by the solvent diffusion technique. Solvent-in-water microemulsion formulations containing water, butyl lactate, lecithin, taurodeoxycholate sodium salt (TDC) or dipotassium glycyrrhizinate (KG), 1,2-propanediol

Lipase-catalyzed transformations for the synthesis of butyl lactate: a comparison between esterification and transesterification.

Domenico Pirozzi et al.

Biotechnology progress, 22(2), 444-448 (2006-04-08)

The alpha-hydroxy esters are increasingly employed in cosmetic, food, and pharmaceutical formulations as they determine reduced skin-irritant effects in comparison with the respective acids, offering similar hygroscopic, emulsifying, and exfoliating properties. The enzymatic synthesis of lactate esters in nonaqueous systems

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Global Trade Item Number

SKU	GTIN
283320-500G	04061826245828
283320-25G	04061831819540
283320-2KG	04061836691714