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Merck
CN

284025

Diethylenetriaminepentaacetic dianhydride

98%

Synonym(s):

N,N-Bis[2-(2,6-dioxomorpholino)ethyl]glycine, DTPA anhydride, DTPA dianhydride

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About This Item

Empirical Formula (Hill Notation):
C14H19N3O8
CAS Number:
Molecular Weight:
357.32
UNSPSC Code:
12162002
NACRES:
NA.23
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1230954
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Product Name

Diethylenetriaminepentaacetic dianhydride, 98%

InChI

1S/C14H19N3O8/c18-10(19)5-15(1-3-16-6-11(20)24-12(21)7-16)2-4-17-8-13(22)25-14(23)9-17/h1-9H2,(H,18,19)

SMILES string

OC(=O)CN(CCN1CC(=O)OC(=O)C1)CCN2CC(=O)OC(=O)C2

InChI key

RAZLJUXJEOEYAM-UHFFFAOYSA-N

assay

98%

form

powder

mp

182-184 °C (lit.)

storage temp.

−20°C

Quality Level

Application

Employed in the synthesis of macrocyclic ligands and lanthanide complexes that are useful as MRI enhancers.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Farid N Faruqu et al.
Theranostics, 9(6), 1666-1682 (2019-05-01)
Extracellular vesicles, in particular exosomes, have recently gained interest as novel drug delivery vectors due to their biological origin and inherent intercellular biomolecule delivery capability. An in-depth knowledge of their in vivo biodistribution is therefore essential. This work aimed to
Inorganic Chemistry, 33, 5794-5794 (1994)
Yongbo Yang et al.
ACS applied materials & interfaces, 9(28), 23450-23457 (2017-06-29)
A bimodal contrast nanoagent was developed by chelating gadolinium ions to 2-[bis[2-[carboxymethyl-[2-oxo-2-(2-sulfanylethyl-amino)ethyl]amino]ethyl]amino]acetic acid (DTDTPA)-modified CuInS
Poorya Najjari Nabi et al.
International journal of biological macromolecules, 174, 185-197 (2021-02-01)
PAMAM dendrimers (PAMs) are a group of polymeric macromolecules with distinctive physicochemical features, which can make them multifunctional theranostic nanoparticles (NPs). This study was designed to examine the impact of mucin-1 aptamer-conjugated NPs which were engineered using PAM for image-guided
C H Paik et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 24(12), 1158-1163 (1983-12-01)
Diethylenetriaminepentaacetic acid (DTPA) was conjugated with a practical concentration (300 micrograms/ml) of antibody to human albumin (Ab) and 1083 17-1A monoclonal colorectal antibody (MAb-17-1A) via an acylation reaction using cyclic DTPA anhydride (cDTPAA). The conjugation reaction was favored as pH

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