285366
Ethyl 2-(4-chlorophenoxy)-2-methylpropionate
99%
Synonym(s):
2-(p-Chlorophenoxy)-2-methylpropionic acid ethyl ester, Clofibrate, Ethyl 2-(p-chlorophenoxy)isobutyrate
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About This Item
Empirical Formula (Hill Notation):
C12H15ClO3
CAS Number:
Molecular Weight:
242.70
PubChem Substance ID:
UNSPSC Code:
12352101
Beilstein/REAXYS Number:
1913459
MDL number:
assay
99%
bp
154-156 °C/20 mmHg (lit.)
density
1.14 g/mL at 25 °C (lit.)
SMILES string
CCOC(=O)C(C)(C)Oc1ccc(Cl)cc1
InChI
1S/C12H15ClO3/c1-4-15-11(14)12(2,3)16-10-7-5-9(13)6-8-10/h5-8H,4H2,1-3H3
InChI key
KNHUKKLJHYUCFP-UHFFFAOYSA-N
Gene Information
human ... PPARA(5465)
Regulatory Information
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Masayuki Yoshikawa et al.
Journal of natural products, 68(9), 1360-1365 (2005-09-27)
The methanolic extract and its n-butanol-soluble fraction from the flowers of the tea plant (Camellia sinensis) were found to suppress serum triglyceride elevation in olive oil-treated mice. From the n-butanol-soluble fraction, three new acylated oleanane-type triterpene oligoglycosides, floratheasaponins A-C (1-3)
Sara Chuang et al.
Journal of medicinal chemistry, 52(17), 5344-5355 (2009-08-12)
Liver-fatty acid binding protein (L-FABP) is found in high levels in enterocytes and is involved in cytosolic solubilization of fatty acids. In addition, L-FABP has been shown to bind endogenous and exogenous lipophilic compounds, suggesting that it may also play
Toshio Morikawa et al.
Journal of natural products, 71(5), 828-835 (2008-03-28)
The methanolic extract and its saponin fraction (methanol-eluted fraction) of the flowers of Bellis perennis were found to suppress serum triglyceride elevation in olive oil-treated mice. From the saponin fraction, seven new triterpene saponins, perennisosides I (1), II (2), III
Leigh V Panlilio et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 37(8), 1838-1847 (2012-03-29)
Experimental drugs that activate α-type peroxisome proliferator-activated receptors (PPARα) have recently been shown to reduce the rewarding effects of nicotine in animals, but these drugs have not been approved for human use. The fibrates are a class of PPARα-activating medications
Clofibrate myopathy: a case report and a review of the literature.
P Rush et al.
Seminars in arthritis and rheumatism, 15(3), 226-229 (1986-02-01)
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