286486
Dodecanoic anhydride
≥98%
Synonym(s):
Lauric anhydride
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About This Item
Linear Formula:
[CH3(CH2)10CO]2O
CAS Number:
Molecular Weight:
382.62
UNSPSC Code:
12352100
PubChem Substance ID:
EC Number:
211-449-9
MDL number:
Assay:
≥98%
Form:
crystals
InChI key
NWADXBLMWHFGGU-UHFFFAOYSA-N
InChI
1S/C24H46O3/c1-3-5-7-9-11-13-15-17-19-21-23(25)27-24(26)22-20-18-16-14-12-10-8-6-4-2/h3-22H2,1-2H3
SMILES string
CCCCCCCCCCCC(=O)OC(=O)CCCCCCCCCCC
assay
≥98%
form
crystals
mp
41-43 °C (lit.)
Gene Information
human ... FNTA(2339), PGGT1B(5229)
General description
The immunogenecity of the material made by coupling dodecanoic anhydride to NH2 groups was studied.
Application
Dodecanoic anhydride was used to chemically conjugate tumor cell membrane in carbonate buffer.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
235.4 °F - closed cup
flash_point_c
113 °C - closed cup
ppe
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Petra Šedová et al.
Carbohydrate polymers, 216, 63-71 (2019-05-03)
The effect of hydrazide linkers on the formation and mechanical properties of hyaluronan hydrogels was intensively evaluated. The reaction kinetics of hydrazone formation was monitored by NMR spectroscopy under physiological conditions where polyaldehyde hyaluronan (unsaturated: ΔHA-CHO, saturated: HA-CHO) was reacted
R L Hunter et al.
Journal of the National Cancer Institute, 54(5), 1157-1163 (1975-05-01)
The covalent conjugation of fatty acid to a tumor cell membrane preparation transformed it from an antigen that enhanced tumor growth to one that suppressed it. A crude cell membrane preparation was made by sequential hypertonic and hypotonic salt extraction
Gordon D Sproul
Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life, 49(4), 241-254 (2019-12-29)
Amino acids and peptides have been demonstrated to form lipoamino acids and lipopeptides under presumed prebiotic conditions, and readily form liposomes. Of the common nucleobases, adenine forms a liponucleobase even below 100 °C. Adenine as well as other nucleobases can also
S B Singh et al.
Journal of immunology (Baltimore, Md. : 1950), 120(3), 734-738 (1978-03-01)
A lipid conjugate of BSA was made by coupling dodecylamine to the COOH groups of BSA (DA-BSA). Studies on the immunogenicity of this material and one made by coupling dodecanoic anhydride to NH2 groups (D-BSA) demonstrated that cell-mediated immunity could
C Bastiancich et al.
Journal of controlled release : official journal of the Controlled Release Society, 225, 283-293 (2016-02-02)
The local delivery of chemotherapeutic agents is a very promising strategy for the treatment of glioblastoma (GBM). Gemcitabine is a chemotherapeutic agent that has a different mechanism of action compared to alkylating agents and shows excellent radio-sensitizing properties. So, we
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