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Merck
CN

288225

Chloro(triethylphosphine)gold(I)

97%, solid

Synonym(s):

(Triethylphosphine)gold(I) chloride

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About This Item

Linear Formula:
(C2H5)3PAuCl
CAS Number:
15529-90-5
Molecular Weight:
350.58
NACRES:
NA.22
PubChem Substance ID:
24857327
UNSPSC Code:
12161600
EC Number:
239-572-3
MDL number:
MFCD00013205

Key Documents

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Product Name

Chloro(triethylphosphine)gold(I), 97%

InChI key

SYBBXLKWGHAVHP-UHFFFAOYSA-M

InChI

1S/C6H15P.Au.ClH/c1-4-7(5-2)6-3;;/h4-6H2,1-3H3;;1H/q;+1;/p-1

SMILES string

Cl[Au].CCP(CC)CC

assay

97%

form

solid

reaction suitability

core: gold, reagent type: catalyst

bp

210 °C/0.03 mmHg (lit.)

mp

84-86 °C (lit.)

Quality Level

100

Related Categories

pictograms

Skull and crossbones
GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
SHBS5989
SHBN0586
SHBJ6628
SHBH1081V
SHBF4326V

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R M Snyder et al.
Molecular pharmacology, 32(3), 437-442 (1987-09-01)
Auranofin (AF) is an orally active chrysotherapeutic agent used for the treatment of rheumatoid arthritis, a self-perpetuating inflammatory disease. Because of reports suggesting that AF and other gold complexes can, under certain circumstances, exacerbate rheumatoid inflammatory lesions in humans and
C J Kirkpatrick et al.
Rheumatology international, 3(2), 49-56 (1983-01-01)
Chondrocyte structure and function under the influence of two gold-containing therapeutic agents, aurothioglucose and triethylphosphine gold, were studied in a monolayer culture system for cultivating lapine articular chondrocytes. The functional parameters investigated were chondrocyte proliferation and the incorporation of 35SO4
Cellular and molecular pharmacology of auranofin and related gold complexes.
S T Crooke et al.
Biochemical pharmacology, 35(20), 3423-3431 (1986-10-15)
N A Malik et al.
Journal of inorganic biochemistry, 12(4), 317-322 (1980-07-01)
Contrasting reactions of the antiarthritic complexes ClAuPEt3 and ClAu(PEt3)2 with blood have been studied by 31P nmr spectroscopy. The monophosphine complex has two binding sites in erythrocytes, probably at the SH groups of glutathione and haemoglobin. The bis complex solidifies
F Märki et al.
Arzneimittel-Forschung, 42(3), 328-333 (1992-03-01)
The effect of several gold complexes on the activity of phospholipase C from human blood platelets was studied in vitro. Aurothiomalate and auranofin--2 agents used for the chrysotherapy of rheumatoid arthritis--, gold chloride, (triethylphosphine)gold chloride, and 5 newly synthesized (triethylphosphine)gold
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