288225
氯(三乙基膦)金(I)
97%, solid
别名:
(三乙基膦)氯化金(I)
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关于此项目
线性分子式:
(C2H5)3PAuCl
化学文摘社编号:
分子量:
350.58
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12161600
EC Number:
239-572-3
MDL number:
产品名称
氯(三乙基膦)金(I), 97%
InChI key
SYBBXLKWGHAVHP-UHFFFAOYSA-M
InChI
1S/C6H15P.Au.ClH/c1-4-7(5-2)6-3;;/h4-6H2,1-3H3;;1H/q;+1;/p-1
SMILES string
Cl[Au].CCP(CC)CC
assay
97%
form
solid
reaction suitability
core: gold, reagent type: catalyst
bp
210 °C/0.03 mmHg (lit.)
mp
84-86 °C (lit.)
Quality Level
Application
signalword
Danger
Hazard Classifications
Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
R M Snyder et al.
Molecular pharmacology, 32(3), 437-442 (1987-09-01)
Auranofin (AF) is an orally active chrysotherapeutic agent used for the treatment of rheumatoid arthritis, a self-perpetuating inflammatory disease. Because of reports suggesting that AF and other gold complexes can, under certain circumstances, exacerbate rheumatoid inflammatory lesions in humans and
C J Kirkpatrick et al.
Rheumatology international, 3(2), 49-56 (1983-01-01)
Chondrocyte structure and function under the influence of two gold-containing therapeutic agents, aurothioglucose and triethylphosphine gold, were studied in a monolayer culture system for cultivating lapine articular chondrocytes. The functional parameters investigated were chondrocyte proliferation and the incorporation of 35SO4
Cellular and molecular pharmacology of auranofin and related gold complexes.
S T Crooke et al.
Biochemical pharmacology, 35(20), 3423-3431 (1986-10-15)
N A Malik et al.
Journal of inorganic biochemistry, 12(4), 317-322 (1980-07-01)
Contrasting reactions of the antiarthritic complexes ClAuPEt3 and ClAu(PEt3)2 with blood have been studied by 31P nmr spectroscopy. The monophosphine complex has two binding sites in erythrocytes, probably at the SH groups of glutathione and haemoglobin. The bis complex solidifies
F Märki et al.
Arzneimittel-Forschung, 42(3), 328-333 (1992-03-01)
The effect of several gold complexes on the activity of phospholipase C from human blood platelets was studied in vitro. Aurothiomalate and auranofin--2 agents used for the chrysotherapy of rheumatoid arthritis--, gold chloride, (triethylphosphine)gold chloride, and 5 newly synthesized (triethylphosphine)gold
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