288225
氯(三乙基膦)金(I)
97%, solid
别名:
(三乙基膦)氯化金(I)
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关于此项目
线性分子式:
(C2H5)3PAuCl
化学文摘社编号:
分子量:
350.58
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12161600
EC Number:
239-572-3
MDL number:
产品名称
氯(三乙基膦)金(I), 97%
InChI key
SYBBXLKWGHAVHP-UHFFFAOYSA-M
InChI
1S/C6H15P.Au.ClH/c1-4-7(5-2)6-3;;/h4-6H2,1-3H3;;1H/q;+1;/p-1
SMILES string
Cl[Au].CCP(CC)CC
assay
97%
form
solid
reaction suitability
core: gold, reagent type: catalyst
bp
210 °C/0.03 mmHg (lit.)
mp
84-86 °C (lit.)
Quality Level
Application
signalword
Danger
Hazard Classifications
Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
G F Rush et al.
Toxicology and applied pharmacology, 90(3), 377-390 (1987-09-30)
Triethylphosphine gold complexes are effective therapeutic agents used for the treatment of rheumatoid arthritis. Many of those molecules are also highly cytotoxic in vitro and can inhibit DNA and protein synthesis. Preliminary experiments have indicated that triethylphosphine gold chloride (TEPAu)
C E Blank et al.
Journal of inorganic biochemistry, 21(1), 21-29 (1984-05-01)
The DNA binding properties of the Au(I)-containing antiarthritic drug Ridaura and related Au(I) complexes have been investigated. Absorption and circular dichroism spectroscopy show that if the gold ion possesses an easily displaced ligand, e.g., Cl- or Br-, Au(I) is capable
G D Hoke et al.
Toxicology and applied pharmacology, 99(1), 50-60 (1989-06-01)
Chlorotriethylphosphine gold(I) (TEPAu) is an organo-gold compound that has therapeutic activity in animal models of rheumatoid arthritis. Initial studies have suggested that TEPAu is a potent cytotoxic compound in vitro against a variety of cultured cell types and isolated hepatocytes.
A A Isab et al.
Journal of inorganic biochemistry, 38(2), 95-100 (1990-02-01)
New compounds having the formula [L-Au-PEt3]Cl (where L = imidazolidine-2-thione(Imt) and 1,3-Diazinane-2-thione(Diaz)) are synthesized. They are characterized by elemental analysis, infrared, 13C and 31P NMR spectroscopy.
M C Grootveld et al.
Journal of inorganic biochemistry, 27(1), 1-15 (1986-05-01)
Reactions of bacterial Fe(III) cyt b562, HbO2, met Hb and met Mb with Et3PAuCl and Et3PAuNO3 (and some related complexes) have been investigated by electronic absorption and EPR and NMR spectroscopy. Except for met Hb, which denatured, the products were
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