291366
N-(2-Chloroethyl)dibenzylamine hydrochloride
97%
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About This Item
Linear Formula:
(C6H5CH2)2NCH2CH2Cl · HCl
CAS Number:
Molecular Weight:
296.23
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
200-234-5
MDL number:
Assay:
97%
InChI key
LZXCEBPGNFLHEQ-UHFFFAOYSA-N
InChI
1S/C16H18ClN.ClH/c17-11-12-18(13-15-7-3-1-4-8-15)14-16-9-5-2-6-10-16;/h1-10H,11-14H2;1H
SMILES string
Cl.ClCCN(Cc1ccccc1)Cc2ccccc2
assay
97%
mp
190-193 °C (lit.)
functional group
amine, chloro, phenyl
General description
N-(2-Chloroethyl)dibenzylamine hydrochloride is also referred as dibenamine. Mechanism of protection against carbon tetrachloride-induced hepatotoxicity produced by pretreatment with [N-(2-chloroethyl) dibenzylamine] hydrochloride has been investigated. It is a powerful adrenergic blocking agent, is known to modify the pharmacological effects of epinephrine.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Effect of dibenamine (N-(2-chloroethyl) dibenzylamine) on the metabolism of radioactive epinephrine.
R W SCHAYER et al.
The Journal of biological chemistry, 202(1), 39-43 (1953-05-01)
Nature of the protection against carbon tetrachloride-induced hepatotoxicity produced by pretreatment with dibenamine (N-(2-chloroethyl)dibenzylamine).
H M Maling et al.
Biochemical pharmacology, 23(10), 1479-1491 (1974-05-15)
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