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Merck
CN

292257

Choline hydroxide solution

46 wt. % in H2O

Synonym(s):

(2-Hydroxyethyl)trimethylammonium hydroxide, (beta-Hydroxyethyl)trimethylammonium hydroxide, 2-Hydroxy-N,N,N-trimethylethanaminium hydroxide

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About This Item

Linear Formula:
HOCH2CH2N(CH3)3OH
CAS Number:
123-41-1
Molecular Weight:
121.18
MDL number:
MFCD00002831
UNSPSC Code:
12352000
PubChem Substance ID:
24857572
NACRES:
NA.22

Key Documents

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form

liquid

Quality Level

200

concentration

46 wt. % in H2O

refractive index

n20/D 1.4304

solubility

water: soluble at 20 °C

density

1.073 g/mL at 25 °C

functional group

amine
hydroxyl

SMILES string

[OH-].C[N+](C)(C)CCO

InChI

1S/C5H14NO.H2O/c1-6(2,3)4-5-7;/h7H,4-5H2,1-3H3;1H2/q+1;/p-1

InChI key

KIZQNNOULOCVDM-UHFFFAOYSA-M

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General description

Choline hydroxide solution is a strong organic base used in pharmaceuticals and chemical manufacturing.

Application

Choline hydroxide solution has been used in the synthesis of choline hexafluoroacetylacetonate that can be used as an extractant along with bis-(trifluoromethylsulfonyl)imide ionic liquid for the homogeneous liquid-liquid extraction of neodymium(III).

Pictograms

Corrosion
GHS05

Signal Word

Danger

Hazard Statements

H314

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1A

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCZ2499
MKCX0076
MKCS3986
MKCS7467
MKAA0765

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Audrey Arnould et al.
Langmuir : the ACS journal of surfaces and colloids, 34(37), 11076-11085 (2018-08-29)
The interfacial and foam properties of a model system based on the mixture between myristic acid and choline hydroxide have been investigated as a function of the molar ratio ( R) between these two components and temperature. The aim of
Inês C Ferreira et al.
Carbohydrate polymers, 247, 116679-116679 (2020-08-25)
This work explores the novelty of dissolving chitin-glucan complex (CGC), from two fungal strains, Komagataella pastoris (CGCP) and Aspergillus niger (CGCKZ) (KiOnutrime-CG™), using biocompatible ionic liquids (ILs). Three cholinium-based ILs were tested, choline acetate, choline propionate and choline hexanoate. Although
Simone Di Muzio et al.
Molecules (Basel, Switzerland), 25(21) (2020-11-01)
We explore the structure of two ionic liquids based on the choline cation and the monoanion of the maleic acid. We consider two isomers of the anion (H-maleate, the cis-isomer and H-fumarate, the trans-isomer) having different physical chemical properties. H-maleate
Xue-Dan Hou et al.
Biotechnology and bioengineering, 112(1), 65-73 (2014-07-30)
In this work, 28 cholinium ionic liquids (ILs), most of which are good solvents for dissolving lignin, were used for rice straw pretreatment to improve subsequent enzymatic hydrolysis. The anion exerted a significant effect on the pretreatment effectiveness of the
Kyung-Eui Park et al.
Bioscience, biotechnology, and biochemistry, 78(6), 981-988 (2014-07-19)
Phospholipase D (PLD) catalyzes the hydrolysis of phosphatidylcholine (PC), the most abundant phospholipids of plasma membrane, resulting in the production of choline and phosphatidic acid (PA). Choline is a precursor of the neurotransmitter acetylcholine, whereas PA functions as an intracellular
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