297682
(R)-(−)-2-Amino-1-propanol
98%
Synonym(s):
D-Alaninol
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About This Item
Linear Formula:
CH3CH(NH2)CH2OH
CAS Number:
Molecular Weight:
75.11
UNSPSC Code:
12352116
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1718866
Assay:
98%
InChI
1S/C3H9NO/c1-3(4)2-5/h3,5H,2,4H2,1H3/t3-/m1/s1
SMILES string
C[C@@H](N)CO
InChI key
BKMMTJMQCTUHRP-GSVOUGTGSA-N
assay
98%
optical activity
[α]19/D −18°, neat
optical purity
ee: 97% (GLC)
refractive index
n20/D 1.4493 (lit.)
bp
166-168 °C (lit.)
density
0.963 g/mL at 20 °C (lit.)
functional group
amine, hydroxyl
General description
(R)-(-)-2-Amino-1-propanol is a chiral secondary amine.
Application
(R)-(-)-2-Amino-1-propanol has been used as a derivatizing agent for gossypol during the analysis of gossypol enantiomers in cottonseed by high-performance liquid chromatography.
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Skin Corr. 1B
Storage Class
8A - Combustible corrosive hazardous materials
wgk
WGK 3
flash_point_f
181.4 °F - closed cup
flash_point_c
83 °C - closed cup
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
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William R Schelman et al.
Investigational new drugs, 32(2), 295-302 (2013-07-19)
A phase I, dose-escalation study of AT-101 with cisplatin and etoposide was conducted to determine the maximum tolerated dose (MTD)/recommended phase 2 dose (RP2D), safety and pharmacokinetics in patients with advanced solid tumors, with an expanded cohort in patients with
Determination of (+)-,(-)-, and total gossypol in cottonseed by high-performance liquid chromatography.
Hron RJ, et al.
Journal of the American Oil Chemists' Society, 76(11), 1351-1355 (1999)
A phase I study of AT-101 with cisplatin and etoposide in patients with advanced solid tumors with an expanded cohort in extensive-stage small cell lung cancer.
Schelman WR, et al.
Investigational New Drugs, 32(2), 295-302 (2014)
A synthetic molecular pentafoil knot.
Ayme J-F, et al.
Nature Chemistry, 4(1), 15-20 (2012)
Neslihan Beyazit et al.
Carbohydrate polymers, 240, 116333-116333 (2020-06-02)
In this work, two new chitosan-Schiff base derivatives (HCS-GSP and LCS-GSP) were synthesized by the condensation reaction of high molecular weight chitosan (HCS) and low molecular weight chitosan (LCS) with (-)-gossypol (GSP), respectively. For this purpose, racemic gossypol was isolated
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