297747
3,6-Dichloro-4-methylpyridazine
97%
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About This Item
Empirical Formula (Hill Notation):
C5H4Cl2N2
CAS Number:
Molecular Weight:
163.00
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
242-794-3
MDL number:
Assay:
97%
InChI key
ROYHWGZNGMXQEU-UHFFFAOYSA-N
InChI
1S/C5H4Cl2N2/c1-3-2-4(6)8-9-5(3)7/h2H,1H3
SMILES string
Cc1cc(Cl)nnc1Cl
assay
97%
bp
149-151 °C/21 mmHg (lit.)
mp
86-88 °C (lit.)
functional group
chloro
Application
3,6-Dichloro-4-methylpyridazine has been used in the synthesis of 7-methyl-2-phenylimidazo[1,2-b]pyridazine-3-carboxylic acid.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Maria Grazia Rimoli et al.
Neuropharmacology, 56(3), 637-646 (2008-12-17)
It is presently unclear whether the antiseizure effects exerted by NSAIDs are totally dependent on COX inhibition or not. To clarify this point we investigated whether 7-methyl-2-phenylimidazo[1,2-b]pyridazine-3-carboxylic acid (DM1) and 6-methoxy-2-phenylimidazo[1,2-b]pyridazine-3-carboxylic acid (DM2), two imidazo[1,2-b]pyridazines structurally related to indomethacin (IDM)
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