299154
L-Methionine-(methyl-13C,d3)
≥99 atom % 13C, ≥99 atom % D, ≥99% (CP)
Synonym(s):
SILAC Amino Acid
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About This Item
Linear Formula:
13CD3SCH2CH2CH(NH2)CO2H
CAS Number:
Molecular Weight:
153.22
NACRES:
NA.12
PubChem Substance ID:
UNSPSC Code:
12352209
MDL number:
Isotopic purity:
≥99 atom % 13C, ≥99 atom % D
Assay:
≥99% (CP)
Mass shift:
M+4
Form:
powder
Quality Level
isotopic purity
≥99 atom % 13C, ≥99 atom % D
assay
≥99% (CP)
form
powder
optical activity
[α]25/D +23.1°, c = 1 in 1 M HCl
technique(s)
protein expression: suitable
mp
284 °C (dec.) (lit.)
mass shift
M+4
SMILES string
[2H][13C]([2H])([2H])SCC[C@H](N)C(O)=O
InChI
1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1/i1+1D3
InChI key
FFEARJCKVFRZRR-ZIHWZSJBSA-N
Application
Used in the methodology of stable isotope tagging of epitopes (SITE) for identification of virus-induced peptides in vaccine development.
Packaging
This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Martin Bachman et al.
Nature chemical biology, 11(8), 555-557 (2015-06-23)
5-Formylcytosine (5fC) is a rare base found in mammalian DNA and thought to be involved in active DNA demethylation. Here, we show that developmental dynamics of 5fC levels in mouse DNA differ from those of 5-hydroxymethylcytosine (5hmC), and using stable
Hugo D Meiring et al.
Molecular & cellular proteomics : MCP, 5(5), 902-913 (2006-01-25)
Identification of peptides presented in major histocompatibility complex (MHC) class I molecules after viral infection is of strategic importance for vaccine development. Until recently, mass spectrometric identification of virus-induced peptides was based on comparative analysis of peptide pools isolated from
Daniele Musiani et al.
Science signaling, 12(575) (2019-04-04)
Protein arginine methyltransferases (PRMTs) catalyze arginine methylation on both chromatin-bound and cytoplasmic proteins. Accumulating evidence supports the involvement of PRMT5, the major type II PRMT, in cell survival and differentiation pathways that are important during development and in tumorigenesis. PRMT5
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 299154-250MG | 04061826657393 |
| 299154-1G | 04061826750025 |