Key Documents

View All Documentation

301450

4-Bromomethyl-6,7-dimethoxycoumarin

Name: 4-Bromomethyl-6,7-dimethoxycoumarin
Brand: ALDRICH

96%

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):

C₁₂H₁₁BrO₄

CAS Number:

88404-25-5

Molecular Weight:

299.12

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

24858188

MDL number:

MFCD00011570

Beilstein/REAXYS Number:

4750487

Assay:

96%

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

Quality Level

100

assay

96%

mp

212-216 °C (lit.)

fluorescence

λ_ex 322; λ_em 395 (Reaction product with acetic acid), λ_ex 354 nm; λ_em 435 nm in methanol

functional group

bromo, ester

SMILES string

COc1cc2OC(=O)C=C(CBr)c2cc1OC

InChI

1S/C12H11BrO4/c1-15-10-4-8-7(6-13)3-12(14)17-9(8)5-11(10)16-2/h3-5H,6H2,1-2H3

InChI key

JGODLBJJCNQFII-UHFFFAOYSA-N

Description

Application

4-Bromomethyl-6,7-dimethoxycoumarin was used as fluorescent labeling reagent for the reversed-phase HPLC separation and detection of carboxylic acids. It was also used as derivatization reagent:

for quantitation of clofibric, bezafibric and fenofibric acids in liver by liquid chromatography
in determination of the concentration of tripeptide glutathione by matrix-assisted laser desorption ionization time-of-flight mass spectrometry
for determination of carboxylic acids in chromatographic detection

pictograms

GHS07

signalword

Warning

hcodes

H302,H315,H319,H335

pcodes

P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Determination of 3-deazaguanine in mice plasma by high-performance liquid chromatography.

B Chandrasekaran et al.

Journal of chromatography, 309(2), 403-408 (1984-08-10)

Quantitation of the glutathione in human peripheral blood by matrix-assisted laser desorption ionization time-of-flight mass spectrometry coupled with micro-scale derivatization.

Chia-Hsien Feng et al.

Analytica chimica acta, 690(2), 209-214 (2011-03-26)

Matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) has been broadly applied to analyze high-molecular-weight compound (such as polymer or proteomic research) but seldom used for low-molecular-weight compound analysis. The objective of this study is the development of a

Simultaneous determination of mycophenolic acid and valproic acid based on derivatization by high-performance liquid chromatography with fluorescence detection.

Yan Zhong et al.

Biomedical chromatography : BMC, 20(4), 319-326 (2005-09-08)

A reliable and validated reversed-phase high-performance liquid chromatography (HPLC) method using fluorescence detection is reported for the simultaneous quantitation of mycophenolic acid (MPA) and valproic acid (VPA) in human plasma. The method is based on the pre-column derivatization of valproic

View All Related Papers

Global Trade Item Number

SKU	GTIN
301450-1G	04061826665398