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Merck
CN

333018

Choline hydroxide solution

45 wt. % in methanol

Synonym(s):

(2-Hydroxyethyl)trimethylammonium hydroxide, (beta-Hydroxyethyl)trimethylammonium hydroxide, 2-Hydroxy-N,N,N-trimethylethanaminium hydroxide

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About This Item

Linear Formula:
HOCH2CH2N(CH3)3OH
CAS Number:
Molecular Weight:
121.18
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352000
MDL number:
Concentration:
45 wt. % in methanol
Form:
liquid
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form

liquid

Quality Level

contains

0.5% paraformaldehyde as stabilizer

concentration

45 wt. % in methanol

refractive index

n20/D 1.4186

density

0.945 g/mL at 25 °C

functional group

amine, hydroxyl

SMILES string

[OH-].C[N+](C)(C)CCO

InChI

1S/C5H14NO.H2O/c1-6(2,3)4-5-7;/h7H,4-5H2,1-3H3;1H2/q+1;/p-1

InChI key

KIZQNNOULOCVDM-UHFFFAOYSA-M

General description

Choline hydroxide solution, also known as choline base, is a strong organic base that can be used in the chemical industry as a solvent, catalyst, and corrosion inhibitor. It can also be used as a stabilizer for quaternary ammonium compounds and as a phase transfer agent in organic synthesis.

Application

Choline hydroxide solution can be used as a catalyst in the efficient conversion of CO2 and 2-aminobenzonitriles to quinazoline-2,4(1H,3H)-dione derivatives.


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Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Carc. 1B - Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1A - STOT SE 1

target_organs

Eyes,Central nervous system

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

73.4 °F - closed cup

flash_point_c

23 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Regulatory Information

危险化学品

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Xue-Dan Hou et al.
Biotechnology and bioengineering, 112(1), 65-73 (2014-07-30)
In this work, 28 cholinium ionic liquids (ILs), most of which are good solvents for dissolving lignin, were used for rice straw pretreatment to improve subsequent enzymatic hydrolysis. The anion exerted a significant effect on the pretreatment effectiveness of the
Kyung-Eui Park et al.
Bioscience, biotechnology, and biochemistry, 78(6), 981-988 (2014-07-19)
Phospholipase D (PLD) catalyzes the hydrolysis of phosphatidylcholine (PC), the most abundant phospholipids of plasma membrane, resulting in the production of choline and phosphatidic acid (PA). Choline is a precursor of the neurotransmitter acetylcholine, whereas PA functions as an intracellular
Yan-Xia An et al.
Bioresource technology, 192, 165-171 (2015-06-01)
Pretreatment of lignocelluloses is a key step in the biorefinery for production of biofuels and valuable platform chemicals. In this work, various lignocelluloses were pretreated using cholinium ionic liquids (ILs) that are wholly composed of biomaterials, and fractionated into carbohydrate-rich



Global Trade Item Number

SKUGTIN
333018-1KG04061826737071