Key Documents

View All Documentation

339652

Cyclen

Name: Cyclen
Brand: ALDRICH

97%

Synonym(s):

1,4,7,10-Tetraazacyclododecane

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):

C₈H₂₀N₄

CAS Number:

294-90-6

Molecular Weight:

172.27

UNSPSC Code:

12162002

NACRES:

NA.23

PubChem Substance ID:

24860658

MDL number:

MFCD00066281

Beilstein/REAXYS Number:

606114

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

Quality Level

100

assay

97%

form

solid

mp

110-113 °C (lit.)

SMILES string

C1CNCCNCCNCCN1

InChI

1S/C8H20N4/c1-2-10-5-6-12-8-7-11-4-3-9-1/h9-12H,1-8H2

InChI key

QBPPRVHXOZRESW-UHFFFAOYSA-N

Description

General description

Cyclen is a microcyclic tetramine that can be used as a ligand that forms a co-ordination linkage with the surface metal cations. It can be used as a synthetic precursor. It can be prepared by S-alkylation of dithiooxamide with an excess amount of bromoethane.

Application

Cyclen is an azamocrocycle, which can be used in the development of fluorescent nanosensors for the detection of metal ions.

pictograms

GHS06,GHS05,GHS09

signalword

Danger

hcodes

H302,H311,H314,H410

pcodes

P260 - P273 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1B

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Lanthanide tags for site-specific ligation to an unnatural amino acid and generation of pseudocontact shifts in proteins.

Choy Theng Loh et al.

Bioconjugate chemistry, 24(2), 260-268 (2013-01-09)

Pseudocontact shifts (PCS) from paramagnetic lanthanide ions present powerful long-range structural restraints for structural biology by NMR spectroscopy, but site-specific tagging of proteins with lanthanides remains a challenge, as most of the available lanthanide tags require proteins with single cysteine

Novel" multipoint" molecular recognition of nucleobases by a new zinc (II) complex of acridine-pendant cyclen (cyclen= 1, 4, 7, 10-tetraazacyclododecane)

Shionoya M, et al.

Journal of the American Chemical Society, 116(9), 3848-3859 (1994)

A new synthesis of cyclen (1, 4, 7, 10-tetraazacyclododecane)

Weisman GR and Reed DP

The Journal of Organic Chemistry, 61(15), 5186-5187 (1996)

View All Related Papers

Global Trade Item Number

SKU	GTIN
339652-250MG	04061826752500