357847
2-Chloro-6-methylpyridine-3-carboxylic acid
97%
Synonym(s):
2-Chloro-6-methyl-3-pyridinecarboxylic acid, 2-Chloro-6-methylnicotinic acid
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About This Item
Empirical Formula (Hill Notation):
C7H6ClNO2
CAS Number:
Molecular Weight:
171.58
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
250-229-7
MDL number:
InChI key
ACQXHCHKMFYDPM-UHFFFAOYSA-N
InChI
1S/C7H6ClNO2/c1-4-2-3-5(7(10)11)6(8)9-4/h2-3H,1H3,(H,10,11)
SMILES string
Cc1ccc(C(O)=O)c(Cl)n1
assay
97%
mp
162-164 °C (lit.)
General description
2-Chloro-6-methylpyridine-3-carboxylic acid (2-Chloro-6-methylnicotinic acid) is a nicotinic acid derivative.
Application
2-Chloro-6-methylpyridine-3-carboxylic acid (2-Chloro-6-methylnicotinic acid) may be used in the synthesis of 6-methyl-2-thiophenoxynicotinic acid, required for the preparation of europium complex for staining the nucleolus of NIH 3T3, HeLa and HDF cells.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Nicotinic acid derivatives. VI. Some transformations of 2-chloro-6-methylnicotinic acid.
P Nantka-Namirski et al.
Polish journal of pharmacology and pharmacy, 26(5), 545-548 (1974-07-01)
Junhua Yu et al.
Journal of the American Chemical Society, 128(7), 2294-2299 (2006-02-16)
A europium complex selectively staining the nucleolus of NIH 3T3, HeLa, and HDF cells is reported. This complex possesses not only the advantage of the long lifetime of europium emission (0.3 ms), but also a chromophore that allows excitation at
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