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Merck
CN

363170

Poly(vinyl alcohol)

Mw 13,000-23,000, 87-89% hydrolyzed

Synonym(s):

PVA

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About This Item

Linear Formula:
[-CH2CHOH-]n
CAS Number:
9002-89-5
NACRES:
NA.23
UNSPSC Code:
12352104
MDL number:
MFCD00081922

Key Documents

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InChI

1S/C2H4O/c1-2-3/h2-3H,1H2

InChI key

IMROMDMJAWUWLK-UHFFFAOYSA-N

form

crystalline powder, crystals or granules, powder

mol wt

Mw 13,000-23,000

falling ball

3.5-4.5 cP, 4 % in H2O(20 °C)(lit.)

Quality Level

200

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General description

Polyvinyl alcohol(PVA) is a linear hydrophilicsynthetic polymer with a monoclinic crystal structure. It can be synthesized via the polymerization of vinyl esters orethers, with subsequent saponification or transesterification. Due to itsexcellent physical and chemical properties, PVA has been widely used inadhesives, fibers, paper industry, drug delivery, and tissue engineering.

Application

PVA is used as a biological reagent to test the dispersion of zinc oxide nanoparticles. PVA has been evaluated as an effective protein resistant material.2 It may be used to stabilize gold colloids of diameter 3-8nm.
Poly(vinyl alcohol) can be used as a secondary template in the synthesis of mesoporous zeolites.

It can be used to prepare a hydrogel template to produce homogeneous microparticles for sustained drug release. PVA is used as a stabilizer in micro-particle preparation due to its high tensile strength and flexibility.

Features and Benefits

  • Good mechanical and chemical stability
  • Non-toxic
  • Tunable hydrophilicity
  • Resistance to solvents Capable of forming films

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

No data available

flash_point_c

No data available

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
MKDB1569
WXBF7749V
WXBF7292V
MKCZ7336
WXBF7015V

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Gold colloidal nanoparticles sized to be suitable precursors for heterogeneous catalysts
Porta F and Prati L
Metal Nanoclusters in Catalysis and Materials Science: The Issue of Size Control, 355-355 (2008)
Zinc oxide nanoparticles as selective killers of proliferating cells.
Taccola L, et al.
International journal of nanomedicine, 6, 1129-1140 (2010)
Nadège Grabowski et al.
International journal of pharmaceutics, 454(2), 686-694 (2013-06-12)
In vitro cytotoxicity and inflammatory response following exposure to nanoparticles (NPs) made of poly(lactide-co-glycolide) (PLGA) have been investigated on A549 human lung epithelial cells. Three different PLGA NPs (230 nm) were obtained using different stabilizers (polyvinyl alcohol, chitosan, or Pluronic(®)
E Fortunati et al.
Carbohydrate polymers, 97(2), 837-848 (2013-08-06)
Cellulose nanocrystals (CNC) extracted from three different sources, namely flax, phormium, and commercial microcrystalline cellulose (MCC) have been used in a polyvinyl alcohol (PVA) matrix to produce anti-bacterial films using two different amounts of silver nanoparticles (0.1 wt% and 0.5
Solmaz Hajizadeh et al.
Journal of chromatography. A, 1274, 6-12 (2013-01-08)
In this work, a new macroporous molecularly imprinted cryogel (MIP composite cryogel) was synthesized by glutaraldehyde cross-linking reaction of poly(vinyl alcohol) (PVA) particles and amino-modified molecularly imprinted core-shell nanoparticles. The MIP core-shell nanoparticles were prepared using propranolol as a template
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