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363464

1-(3-Chlorophenyl)-4-(3-chloropropyl)piperazine monohydrochloride

Name: 1-(3-Chlorophenyl)-4-(3-chloropropyl)piperazine monohydrochloride
Brand: ALDRICH

97%

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About This Item

Empirical Formula (Hill Notation):

C₁₃H₁₈Cl₂N₂ · HCl

CAS Number:

52605-52-4

Molecular Weight:

309.66

NACRES:

NA.22

PubChem Substance ID:

24862198

UNSPSC Code:

12352100

EC Number:

258-038-0

MDL number:

MFCD00067039

Assay:

97%

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Properties

Quality Level

100

assay

97%

mp

198-203 °C (lit.)

functional group

chloro

SMILES string

Cl[H].ClCCCN1CCN(CC1)c2cccc(Cl)c2

InChI

1S/C13H18Cl2N2.ClH/c14-5-2-6-16-7-9-17(10-8-16)13-4-1-3-12(15)11-13;/h1,3-4,11H,2,5-10H2;1H

InChI key

JVLRNANYLVRULL-UHFFFAOYSA-N

Description

General description

1-(3-Chlorophenyl)-4-(3-chloropropyl)piperazine monohydrochloride is present as impurity in nefazodone hydrochloride (pharmaceutical formulation). Synthesis of 1-(3-chlorophenyl)-4-(3-chloropropyl)piperazine monohydrochloride is reported.

pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number

01908AX

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Synthesis of 1-(3-Chlorophenyl)-4-(3-Chloropropyl)-Piperazine Hydrochloride.

Fine Chemicals / ????, 35(5) (2005)

LC determination and purity evaluation of nefazodone HCl in bulk drug and pharmaceutical formulations.

D Sreenivas Rao et al.

Journal of pharmaceutical and biomedical analysis, 26(4), 629-636 (2001-08-23)

A simple, selective and reproducible reversed-phase liquid chromatography (LC) method has been developed for the quantitative determination of nefazodone hydrochloride (I) in the presence of its related impurities, namely 5-ethyl-4-(2-phenoxyethyl)-2H-1,2,4-triazol-3-(4H)one (II), 1-(3-chlorophenyl)-4-(3-chloropropyl) piperazine hydrochloride (III) and 1,1(1)-trimethylene-bis[4-(3-chlorophenyl) piperazine] hydrochloride (IV).

Global Trade Item Number

SKU	GTIN
363464-25G	04061832249018