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363634

Semicarbazide

Name: Semicarbazide
Brand: ALDRICH

6 wt. % (on silica gel)

Synonym(s):

Aminourea, Hydrazinecarboxamide, Isosemicarbazide

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About This Item

Linear Formula:

H₂NCONHNH₂

CAS Number:

57-56-7

Molecular Weight:

75.07

NACRES:

NA.22

PubChem Substance ID:

24862206

UNSPSC Code:

12352125

MDL number:

MFCD00042824

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Properties

form

powder

Quality Level

100

composition

, 6 wt. % (on silica gel)

SMILES string

NNC(N)=O

InChI

1S/CH5N3O/c2-1(5)4-3/h3H2,(H3,2,4,5)

InChI key

DUIOPKIIICUYRZ-UHFFFAOYSA-N

Description

Application

Antibacterial activity: Semicarbazide derivatives, specifically thiosemicarbazide, exhibit significant antibacterial properties influenced by substituent position. This underscores its application in pharmaceutical synthesis and microbial resistance studies (Janowska et al., 2024).
Solar cell performance: The application of semicarbazide hydrochloride in suppressing deep-level traps significantly improves the efficiency of tin-based perovskite solar cells, highlighting its potential in energy materials research (Jia et al., 2023).

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Stereochemistry and cofactor identity status of semicarbazide-sensitive amine oxidases.

M M Palcic et al.

Progress in brain research, 106, 41-47 (1995-01-01)

The relationship between the soluble copper topaquinone amine oxidases, the membrane bound semicarbazide-sensitive amine oxidases and lysyl oxidase remains unclear. The stereochemical course of substrate oxidation has been determined for each enzyme type and these studies suggest that SSAO and

Aberrant expression of the S1P regulating enzymes, SPHK1 and SGPL1, contributes to a migratory phenotype in OSCC mediated through S1PR2.

Sathya Narayanan Patmanathan et al.

Scientific reports, 6, 25650-25650 (2016-05-11)

Oral squamous cell carcinoma (OSCC) is a lethal disease with a 5-year mortality rate of around 50%. Molecular targeted therapies are not in routine use and novel therapeutic targets are required. Our previous microarray data indicated sphingosine 1-phosphate (S1P) metabolism

Vascular adhesion protein-1 is elevated in primary sclerosing cholangitis, is predictive of clinical outcome and facilitates recruitment of gut-tropic lymphocytes to liver in a substrate-dependent manner.

Palak J Trivedi et al.

Gut, 67(6), 1135-1145 (2017-04-22)

Primary sclerosing cholangitis (PSC) is the classical hepatobiliary manifestation of IBD. This clinical association is linked pathologically to the recruitment of mucosal T cells to the liver, via vascular adhesion protein (VAP)-1-dependent enzyme activity. Our aim was to examine the

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Global Trade Item Number

SKU	GTIN
363634-100G	04061831825145
363634-25G	04061831825152