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Merck
CN

372846

Poly(2-ethyl-2-oxazoline) 5-7 cSt

Synonym(s):

Poly(2-ethyl-2-oxazoline), PEOX, POx, PetOx, poly 2-ethyloxazoline, polyethyloxazoline

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About This Item

Linear Formula:
[-N(COC2H5)CH2CH2-]n
CAS Number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23
MDL number:
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form

solid

Quality Segment

mol wt

average Mw ~50,000

feature

hydrophilic

refractive index

n20/D 1.52

viscosity

5-7 cSt, 10 % in water(100 °F)

transition temp

softening point 110-120 °C (Vicat, ASTM D 1525-82), Tg 69-71 °C

density

1.14 g/mL at 25 °C (lit.)

PDI

3‑4

InChI

1S/C5H9NO/c1-2-5-6-3-4-7-5/h2-4H2,1H3

InChI key

NYEZZYQZRQDLEH-UHFFFAOYSA-N

Application

This Poly(2-ethyl-2-oxazoline) polymer is amorphous and water soluble with good temperature stability. Jordan and coworkers showed biocompatibility, no accumulation in tissue, and rapid clearance from the bloodstream. End-group modified poly(2-ethyl-2-oxazoline)s have been conjugated to peptides, and were shown as versatile alternatives to poly(ethylene glycol) (PEG) for both protein and small drug conjugation.

Potential substitute for poly(vinyl alcohol) and poly(vinyl pyrrolidone). Adhesion promoter in coatings. Heat sealing and remoistenable hot-melt adhesive

Features and Benefits

Nonionic, water-soluble thermoplastic. Better heat stability than poly(vinyl alcohol). Good melt flow, shear stability and Newtonian characteristics. Water is a room temperature Theta solvent.

Physical form

N-propionyl substituted linear polyethylenimine


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)



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