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Merck
CN

376914

Poly(methyl methacrylate-co-methacrylic acid)

average Mw ~34,000 by GPC, average Mn ~15,000 by GPC

Synonym(s):

Poly(methacrylic acid-co-methyl methacrylate)

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About This Item

CAS Number:
25086-15-1
UNSPSC Code:
12162002
PubChem Substance ID:
24863477
NACRES:
NA.23
MDL number:
MFCD00243185

Key Documents

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SMILES string

O(C)C(=O)C(=C)C.OC(=O)C(=C)C

InChI

1S/C5H8O2.C4H6O2/c1-4(2)5(6)7-3;1-3(2)4(5)6/h1H2,2-3H3;1H2,2H3,(H,5,6)

InChI key

IWVKTOUOPHGZRX-UHFFFAOYSA-N

feed ratio

1:0.016 (methyl methacrylate:methacrylic acid)

mol wt

average Mn ~15,000 by GPC, average Mw ~34,000 by GPC

inherent viscosity

0.19 dL/g(lit.)

transition temp

Tg 105 °C

Related Categories

Application

  • Ultrafine Nanoparticles of Poly(Methyl Methacrylate-co-Methacrylic Acid) Loaded with Aspirin: This study focuses on the preparation and potential therapeutic applications of biocompatible nanoparticles loaded with aspirin, highlighting their suitability for medical use (López-Muñoz et al., 2019).
  • Biocompatible and biodegradable ultrafine nanoparticles of poly (methyl methacrylate-co-methacrylic acid) prepared via semicontinuous heterophase: Discusses the synthesis of biodegradable nanoparticles for potential biomedical applications, emphasizing their eco-friendly nature and suitability for drug delivery systems (Saade et al., 2016).
  • Synthesis and characteristics of poly(methyl methacrylate‐co‐methacrylic acid)/poly(methacrylic acid‐co‐N‐isopropylacrylamide) thermosensitive semi‐hollow latex: Explores the unique properties of thermosensitive latex particles for advanced material applications, potentially useful in smart drug delivery systems (Lee et al., 2014).
  • Preparation and release behavior of poly(methyl methacrylate-co-methacrylic acid)-based electrospun nanofibrous mats loaded with doxorubicin: Examines the use of polymeric nanofibers for controlled drug release, particularly for cancer treatment, demonstrating the versatility of poly(methyl methacrylate-co-methacrylic acid) in pharmaceutical applications (López-Muñoz et al., 2023).

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
MKBG3620V
MKBG3616V
MKBD4926
MKBD4927
02314EJ

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Fatima Rasool et al.
Acta poloniae pharmaceutica, 69(2), 347-353 (2012-05-10)
Metoprolol, a cardioselective β-blocker, is well absorbed in colon after oral administration with mean elimination half life of 3 h with bioavailability 50% due to extensive first pass effect, thus it was aimed to develop its modified release dosage form
Kateřina Dvořáčková et al.
Medicina (Kaunas, Lithuania), 48(4), 192-202 (2012-07-28)
Eudragit® NM was investigated as a matrix former in combination with microcrystalline cellulose as an insoluble filler for preparing controlled-release tablets containing model drugs with different solubility. Three sets of matrix tablets differing in the drug-to-filler ratio (1:1, 2:1, and
Katia P Seremeta et al.
Colloids and surfaces. B, Biointerfaces, 102, 441-449 (2012-09-27)
The design of simple and scalable drug delivery systems to target the central nervous system (CNS) could represent a breakthrough in the addressment of the HIV-associated neuropathogenesis. The intranasal (i.n.) route represents a minimally invasive strategy to surpass the blood-brain
Rouslan I Moustafine et al.
International journal of pharmaceutics, 439(1-2), 17-21 (2012-10-09)
Interpolymer interactions between the countercharged methacrylate copolymers Eudragit(®) RL 30D (polycation) and Eudragit(®) FS 30D (polyanion), were investigated in conditions mimicking the gastrointestinal environment. The formation of inter-macromolecular ionic bonds between Eudragit(®) RL 30D and Eudragit(®) FS 30D was investigated
Pravin K Pawar et al.
Acta pharmaceutica (Zagreb, Croatia), 62(1), 93-104 (2012-04-05)
The objective of the present investigation was to prepare and evaluate ocular inserts of moxifloxacin. An ocular insert was made from an aqueous dispersion of moxifloxacin, sodium alginate, polyvinyl alcohol, and dibutyl phthalate by the film casting method. The ocular
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