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Merck
CN

376914

聚（甲基丙烯酸甲酯- co -甲基丙烯酸）

average Mw ~34,000 by GPC, average Mn ~15,000 by GPC

别名:

甲基丙烯酸-甲基丙烯酸甲酯共聚物

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关于此项目

化学文摘社编号:
25086-15-1
UNSPSC Code:
12162002
PubChem Substance ID:
24863477
NACRES:
NA.23
MDL number:
MFCD00243185

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产品名称

聚（甲基丙烯酸甲酯- co -甲基丙烯酸）, average Mw ~34,000 by GPC, average Mn ~15,000 by GPC

SMILES string

O(C)C(=O)C(=C)C.OC(=O)C(=C)C

InChI

1S/C5H8O2.C4H6O2/c1-4(2)5(6)7-3;1-3(2)4(5)6/h1H2,2-3H3;1H2,2H3,(H,5,6)

InChI key

IWVKTOUOPHGZRX-UHFFFAOYSA-N

feed ratio

1:0.016 (methyl methacrylate:methacrylic acid)

mol wt

average Mn ~15,000 by GPC
average Mw ~34,000 by GPC

inherent viscosity

0.19 dL/g(lit.)

transition temp

Tg 105 °C

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相关类别

Application

  • 负载阿司匹林的聚（甲基丙烯酸甲酯-co-甲基丙烯酸）超细纳米颗粒：该研究关注了负载阿司匹林的生物相容性纳米颗粒的制备和潜在治疗应用，重点介绍了其对医疗用途的适用性（López-Muñoz et al., 2019）。
  • 通过半连续多相制备的聚（甲基丙烯酸甲酯-co-甲基丙烯酸）的生物相容性、可生物降解超细纳米颗粒：讨论了具有潜在生物医学应用的可生物降解超细纳米颗粒的合成 ，重点介绍了其在药物递送体系中的环保特性和稳定性（Saade et al., 2016）。
  • 聚（甲基丙烯酸甲酯-co-甲基丙烯酸）/聚（甲基丙烯酸-co-N-异丙基丙烯酰胺）热敏性半中空乳胶的合成和特征：探讨了用于先进材料应用的热敏性乳胶颗粒的独特性质 ，其在智能药物递送系统中的潜在用途（Lee et al., 2014）。
  • 负载阿霉素的聚（甲基丙烯酸甲酯-co-甲基丙烯酸）基静电纺丝纳米纤维垫的制备和释放行为：考察了聚合物纳米纤维在受控药物释放（特别是癌症治疗）中的用途，体现了聚（甲基丙烯酸甲酯-co-甲基丙烯酸）在药物应用中的多功能性（López-Muñoz et al., 2023）。

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
MKBG3620V
MKBG3616V
MKBD4926
MKBD4927
02314EJ

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Yan Zhang et al.
International journal of pharmaceutics, 436(1-2), 341-350 (2012-07-07)
In the present study thiolated Eudragit L100 (Eul) based polymeric nanoparticles (NPs) were employed to develop an oral insulin delivery system. Sulfydryl modification was achieved by grafting cysteine to the carboxylic acid group of Eudragit L100, which displayed maximum conjugate
Pravin K Pawar et al.
Acta pharmaceutica (Zagreb, Croatia), 62(1), 93-104 (2012-04-05)
The objective of the present investigation was to prepare and evaluate ocular inserts of moxifloxacin. An ocular insert was made from an aqueous dispersion of moxifloxacin, sodium alginate, polyvinyl alcohol, and dibutyl phthalate by the film casting method. The ocular
Prathap Nagaraja Shastri et al.
Drug development and industrial pharmacy, 39(2), 164-175 (2012-05-18)
Oral delivery of proteins has been a challenging as well as rapidly developing field. To implement mixture design of experiment to develop enteric-coated microparticles containing bovine serum albumin. Microparticles were prepared using Buchi Spray Dryer 191. Simplex lattice mixture design
Suprita A Tawde et al.
Vaccine, 30(38), 5675-5681 (2012-07-04)
Ovarian cancer is the fifth most leading cause of cancer related deaths in women in the US. Customized immunotherapeutic strategies may serve as an alternative method to control the recurrence or progression of ovarian cancer and to avoid severe adverse
Martins Emeje et al.
Acta pharmaceutica (Zagreb, Croatia), 62(1), 71-82 (2012-04-05)
Sustained release (SR) dosage forms enable prolonged and continuous deposition of the drug in the gastrointestinal (GI) tract and improve the bioavailability of medications characterized by a narrow absorption window. In this study, a new strategy is proposed for the
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