376914
聚（甲基丙烯酸甲酯- co -甲基丙烯酸）
average Mw ~34,000 by GPC, average Mn ~15,000 by GPC
别名:
甲基丙烯酸-甲基丙烯酸甲酯共聚物
SMILES string
O(C)C(=O)C(=C)C.OC(=O)C(=C)C
InChI
1S/C5H8O2.C4H6O2/c1-4(2)5(6)7-3;1-3(2)4(5)6/h1H2,2-3H3;1H2,2H3,(H,5,6)
InChI key
IWVKTOUOPHGZRX-UHFFFAOYSA-N
feed ratio
1:0.016 (methyl methacrylate:methacrylic acid)
mol wt
average Mn ~15,000 by GPC, average Mw ~34,000 by GPC
inherent viscosity
0.19 dL/g(lit.)
transition temp
Tg 105 °C
Application
- 负载阿司匹林的聚（甲基丙烯酸甲酯-co-甲基丙烯酸）超细纳米颗粒：该研究关注了负载阿司匹林的生物相容性纳米颗粒的制备和潜在治疗应用，重点介绍了其对医疗用途的适用性（López-Muñoz et al., 2019）。
- 通过半连续多相制备的聚（甲基丙烯酸甲酯-co-甲基丙烯酸）的生物相容性、可生物降解超细纳米颗粒：讨论了具有潜在生物医学应用的可生物降解超细纳米颗粒的合成 ，重点介绍了其在药物递送体系中的环保特性和稳定性（Saade et al., 2016）。
- 聚（甲基丙烯酸甲酯-co-甲基丙烯酸）/聚（甲基丙烯酸-co-N-异丙基丙烯酰胺）热敏性半中空乳胶的合成和特征：探讨了用于先进材料应用的热敏性乳胶颗粒的独特性质 ，其在智能药物递送系统中的潜在用途（Lee et al., 2014）。
- 负载阿霉素的聚（甲基丙烯酸甲酯-co-甲基丙烯酸）基静电纺丝纳米纤维垫的制备和释放行为：考察了聚合物纳米纤维在受控药物释放（特别是癌症治疗）中的用途，体现了聚（甲基丙烯酸甲酯-co-甲基丙烯酸）在药物应用中的多功能性（López-Muñoz et al., 2023）。
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Medicina (Kaunas, Lithuania), 48(4), 192-202 (2012-07-28)
Eudragit® NM was investigated as a matrix former in combination with microcrystalline cellulose as an insoluble filler for preparing controlled-release tablets containing model drugs with different solubility. Three sets of matrix tablets differing in the drug-to-filler ratio (1:1, 2:1, and
Katia P Seremeta et al.
Colloids and surfaces. B, Biointerfaces, 102, 441-449 (2012-09-27)
The design of simple and scalable drug delivery systems to target the central nervous system (CNS) could represent a breakthrough in the addressment of the HIV-associated neuropathogenesis. The intranasal (i.n.) route represents a minimally invasive strategy to surpass the blood-brain
Rouslan I Moustafine et al.
International journal of pharmaceutics, 439(1-2), 17-21 (2012-10-09)
Interpolymer interactions between the countercharged methacrylate copolymers Eudragit(®) RL 30D (polycation) and Eudragit(®) FS 30D (polyanion), were investigated in conditions mimicking the gastrointestinal environment. The formation of inter-macromolecular ionic bonds between Eudragit(®) RL 30D and Eudragit(®) FS 30D was investigated
Huasheng Yang et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 36(11), 1427-1430 (2012-07-12)
Using Apocynum venetum as a model drug to prepare pulsed-release tablets based on diffusion, swelling, osmotic pressure mechanism and to evaluate the release characteristics. The pulsatile release tablets were prepared by film coating methods using HPMC E5 and Eudragit The
Pravin K Pawar et al.
Acta pharmaceutica (Zagreb, Croatia), 62(1), 93-104 (2012-04-05)
The objective of the present investigation was to prepare and evaluate ocular inserts of moxifloxacin. An ocular insert was made from an aqueous dispersion of moxifloxacin, sodium alginate, polyvinyl alcohol, and dibutyl phthalate by the film casting method. The ocular
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