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Merck
CN

388513

5,8-Dihydroxy-1,4-naphthoquinone

technical grade

Synonym(s):

Naphthazarin

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About This Item

Empirical Formula (Hill Notation):
C10H6O4
CAS Number:
Molecular Weight:
190.15
UNSPSC Code:
12352103
NACRES:
NA.23
PubChem Substance ID:
EC Number:
207-495-4
Beilstein/REAXYS Number:
880561
MDL number:
Technical Service
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grade

technical grade

Quality Level

mp

220-230 °C (lit.)

SMILES string

Oc1ccc(O)c2C(=O)C=CC(=O)c12

InChI

1S/C10H6O4/c11-5-1-2-6(12)10-8(14)4-3-7(13)9(5)10/h1-4,11-12H

InChI key

RQNVIKXOOKXAJQ-UHFFFAOYSA-N



Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Brígida R Pinho et al.
PloS one, 6(8), e24098-e24098 (2011-09-03)
The search of new anti-inflammatory drugs has been a current preoccupation, due to the need of effective drugs, with less adverse reactions than those used nowadays. Several naphthoquinones (plumbagin, naphthazarin, juglone, menadione, diosquinone and 1,4-naphthoquinone), plus p-hydroquinone and p-benzoquinone were
Régis Millet et al.
Journal of medicinal chemistry, 48(22), 7024-7039 (2005-10-28)
The human selenoprotein thioredoxin reductase is involved in antioxidant defense and DNA synthesis. As increased thioredoxin reductase levels are associated with drug sensitivity to cisplatin and drug resistance in tumor cells, this enzyme represents a promising target for the development
An efficient formal synthesis of the human telomerase inhibitor (+/-)-gamma-rubromycin.
Dominea C K Rathwell et al.
Angewandte Chemie (International ed. in English), 48(43), 7996-8000 (2009-08-01)



Global Trade Item Number

SKUGTIN
388513-1G04061831969399