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Sigma-Aldrich

D-Glucose-13C6

≥99 atom % 13C, ≥99% (CP)

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Synonym(s):
Labeled Glucose, D-Glucose-ul-13C, Dextrose-13C6
Empirical Formula (Hill Notation):
13C6H12O6
CAS Number:
110187-42-3
Molecular Weight:
186.11
MDL number:
MFCD00037544
PubChem Substance ID:
24864278

isotopic purity

≥99 atom % 13C

Assay

≥99% (CP)

form

powder

optical activity

[α]25/D +52.0°, c = 2 in H2O (trace NH4OH)

technique(s)

bio NMR: suitable
protein expression: suitable
protein purification: suitable

mp

150-152 °C (lit.)

mass shift

M+6

SMILES string

O[13CH2][13C@H]1O[13C@H](O)[13C@H](O)[13C@@H](O)[13C@@H]1O

InChI

1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6?/m1/s1/i1+1,2+1,3+1,4+1,5+1,6+1

InChI key

WQZGKKKJIJFFOK-NYKRWLDMSA-N

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Application

D-Glucose-13C6 has been used:
  • for de novo fatty acid (FA) synthesis
  • as a component in tracing media for the analysis of stable isotope tracer
  • in minimal media for recombinant protein production
  • for cell suspension

Biochem/physiol Actions

D-Glucose-13C6 functions as a tracer and helps to access glucose kinetics in vivo.

Packaging

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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RSK Regulates PFK-2 Activity to Promote Metabolic Rewiring in Melanoma
Houles T, et al.
Cancer Research, canres-ca2215 (2018)
Metabolic profiling reveals a coordinated response of isolated lamb's (Valerianella locusta, L.) lettuce cells to sugar starvation and low oxygen stress
Victor BMM, et al.
Postharvest biology and technology, 126, 23-33 (2017)
Zoran Dinev et al.
Carbohydrate research, 341(10), 1743-1747 (2006-04-11)
A simple gram-scale synthesis of uridine diphospho(13C6)glucose is presented from D-(13C6)glucose. The critical step uses a 1H-tetrazole-catalyzed coupling of 2,3,4,6-tetra-O-acetyl-alpha-D-glucopyranosyl-1-phosphate and UMP-morpholidate. The uridine diphospho(13C6)glucose was used in the structural identification of (1-->3)-beta-D-glucan from Lolium multiflorum.
Y Oda et al.
Biochemistry, 33(17), 5275-5284 (1994-05-03)
All of the individual carboxyl groups (the side-chain carboxyl groups of Asp and Glu, and the C-terminal alpha-carboxyl group) in Escherichia coli ribonuclease HI, which is an enzyme that cleaves the RNA strand of a RNA/DNA hybrid, were pH-titrated, and
Dietary Sugars: Chemistry, Analysis, Function and Effects (2012)
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