39205
Dimethylaminomethyl-polystyrene
200-400 mesh particle size, extent of labeling: 3-4 mmol/g base loading, matrix crosslinked with 2% DVB
Synonym(s):
Benzyldimethylamine polymer-bound, Copolymer of styrene and divinylbenzene, dimethylaminomethylated, Polystyrene crosslinked with divinylbenzene, dimethylaminomethylated
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About This Item
reaction suitability
reaction type: solution phase peptide synthesis, reactivity: proton reactive
extent of labeling
3-4 mmol/g base loading
impurities
≤0.5 mmol/g Cl- (resin)
matrix
crosslinked with 2% DVB
particle size
200-400 mesh
SMILES string
[X]C(CC(CC(C[X])c3ccc(cc3)CN(C)C)c2ccc(cc2)CN(C)C)c1ccc(cc1)CN(C)C
General description
Dimethylaminomethyl-polystyrene, also known as benzyldimethylamine, is a polystyrene-supported resin crosslinked with divinylbenzene that is commonly used in solution phase peptide synthesis.
Application
Dimethylaminomethyl-polystyrene is used as a resin to synthesize hydrophobic dipeptides such as bis-phenylalanines that can be used in the study of peptide and protein aggregation. Additionally, it can also be utilized for neutralizing acidic solution in a reaction mixture due to its proton reactive nature.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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