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394866

Supelco

N-Methyl-N-(trimethylsilyl)trifluoroacetamide

synthesis grade

Synonym(s):

N-Trimethylsilyl-N-methyl trifluoroacetamide, MSTFA

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5 ML
CN¥1,496.38
10 X 1 ML
CN¥2,296.40
25 ML
CN¥4,574.30

CN¥1,496.38

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5 ML
CN¥1,496.38
10 X 1 ML
CN¥2,296.40
25 ML
CN¥4,574.30

About This Item

Linear Formula:
CF3CON(CH3)Si(CH3)3
CAS Number:
24589-78-4
Molecular Weight:
199.25
Beilstein:
1941550
EC Number:
246-331-6
MDL number:
MFCD00000411
UNSPSC Code:
41115710
PubChem Substance ID:
24864622
NACRES:
NA.22

CN¥1,496.38

In StockDetails

Request a Bulk Order

grade

derivatization grade ((GC derivatization))
synthesis grade

Quality Level

100

vapor density

>1 (vs air)

vapor pressure

8.8 mmHg ( 27 °C)

Assay

≥98%

form

liquid

reaction suitability

reagent type: derivatization reagent
reaction type: Silylations

refractive index

n20/D 1.38 (lit.)

bp

130-132 °C (lit.)

density

1.075 g/mL at 25 °C (lit.)

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N-Methyl-N-(trimethylsilyl)trifluoroacetamide synthesis grade

394866

N-Methyl-N-(trimethylsilyl)trifluoroacetamide

N-Methyl-N-(trimethylsilyl)trifluoroacetamide derivatization grade (GC derivatization), LiChropur™, ≥98.5%

69479

N-Methyl-N-(trimethylsilyl)trifluoroacetamide

N-Methyl-N-(trimethylsilyl)trifluoroacetamide with 1% trimethylchlorosilane derivatization grade (GC derivatization), LiChropur™

69478

N-Methyl-N-(trimethylsilyl)trifluoroacetamide with 1% trimethylchlorosilane

N-Methyl-N-trimethylsilyltrifluoroacetamide activated III derivatization grade (GC derivatization), LiChropur™, activated with imidazole

12124

N-Methyl-N-trimethylsilyltrifluoroacetamide activated III

assay

≥98%

assay

≥98.5% (GC)

assay

≥97.0%

assay

-

reaction suitability

reagent type: derivatization reagent
reaction type: Silylations

reaction suitability

reagent type: derivatization reagent
reaction type: Silylations

reaction suitability

reagent type: derivatization reagent
reaction type: Silylations

reaction suitability

reagent type: derivatization reagent
reaction type: Silylations

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

form

liquid

form

liquid

form

liquid

form

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

storage temp.

2-8°C

bp

130-132 °C (lit.)

bp

130-132 °C (lit.)

bp

-

bp

-

General description

N-Methyl-N-(trimethylsilyl)trifluoroacetamide (MSTFA) is a derivatizing reagent. It can be used as alternatives to diazomethane.[1]

Application

Silylating agent used to form volatile derivatives for GC-MS analysis.[2]
Improved silylation procedure for simultaneous detection of steroid hormones 17-α-ethynylestradiol and estrone.[3]

Other Notes

Reagent for trimethylsilyl.

related product

Product No.
Description
Pricing

Pictograms

FlameExclamation mark
GHS02,GHS07

Signal Word

Warning

Hazard Statements

H226,H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

77.0 °F - closed cup

Flash Point(C)

25 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

危险化学品
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    Certificates of Analysis (COA)

    Lot/Batch Number
    BCCM7637
    BCCL3951
    BCCM1869
    BCCK4757
    BCCK9225

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    Tina Kosjek et al.
    Environment international, 31(5), 679-685 (2005-05-25)
    Pharmacologically active substances used to treat human and animal illnesses can enter the aquatic environment via effluents from wastewater treatment plants or in the case of veterinary drugs directly through liquid manure discharge. Some of these substances enter the environment
    Hee-Kyung Jeon et al.
    Journal of chromatography. A, 1131(1-2), 192-202 (2006-08-08)
    A novel method has been developed to simultaneously determine and quantify seven organic UV filters employing liquid (solid)-liquid extraction, derivatization with N-methyl-N-(trimethylsilyl) trifluoroacetamide (MSTFA) and gas chromatography with mass spectrometric detection in various environmental matrices. The UV filters determined were:
    L Damasceno et al.
    Journal of mass spectrometry : JMS, 35(11), 1285-1294 (2000-12-13)
    An evaluation of derivatization procedures for the detection of beta(2)-agonists is presented. The study was performed with the beta(2)-agonists bambuterol, clenbuterol, fenoterol, formoterol, salbutamol, salmeterol and terbutaline. Different derivatizating agents were employed, aiming to obtain derivatives with high selectivity to
    Stina K Lien et al.
    Journal of chromatography. A, 1247, 118-124 (2012-06-15)
    GC-MS analysis of silylated metabolites is a sensitive method that covers important metabolite groups such as sugars, amino acids and non-amino organic acids, and it has become one of the most important analytical methods for exploring the metabolome. Absolute quantitative
    E Teixidó et al.
    Journal of chromatography. A, 1135(1), 85-90 (2006-10-03)
    A new, simple and selective method for the analysis of 5-hydroxymethylfurfural (HMF) in foods by gas chromatography coupled to mass spectrometry (GC-MS) is proposed. Several derivatising procedures based on the formation of an HMF silylated derivative using different reagents were
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