397210
2-Amino-5-chloro-2′-fluorobenzophenone
98%
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About This Item
Linear Formula:
H2NC6H3(Cl)C(O)C6H4F
CAS Number:
Molecular Weight:
249.67
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
212-316-8
MDL number:
Product Name
2-Amino-5-chloro-2′-fluorobenzophenone, 98%
InChI key
GTGMXPIQRQSORU-UHFFFAOYSA-N
InChI
1S/C13H9ClFNO/c14-8-5-6-12(16)10(7-8)13(17)9-3-1-2-4-11(9)15/h1-7H,16H2
SMILES string
Nc1ccc(Cl)cc1C(=O)c2ccccc2F
assay
98%
mp
95-98 °C (lit.)
functional group
chloro
fluoro
ketone
Quality Level
Application
2-Amino-5-chloro-2′-fluorobenzophenone is suitable electrophilic coupling reagent for the determination of iron(III) in environmental waters, soils and industrial effluent samples. It may be used in the synthesis of following:
- 2,4-disubstituted quinolones, via Meyer-Schuster rearrangement
- 6-chloro-2-methyl-4-(2-fluorophenyl) quinazoline
- N-desalkylflurazepam
- benzotriazepines
- diazepam-related benzodiazepines.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Bhawana Sati et al.
Acta pharmaceutica (Zagreb, Croatia), 63(3), 385-396 (2013-10-25)
During the manufacture of bulk drug midazolam various impurities arised that can be the related products or degradation products. Structures of eight impurities that can arise during the manufacture of bulk drug midazolam were proposed. In the present work, synthesis
Ionic liquid-an efficient recycalable system for the synthesis of 2, 4-disubstituted quinolines via Meyer-Schuster rearrangement.
Saqrma R and Prajapati D.
Synlett, 19, 3001-3005 (2008)
Journal of the American Chemical Society, 112, 3969-3969 (1990)
J. Chem. Res. Synop., 2-2 (1991)
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