406902
6-Mercaptopyridine-3-carboxylic acid
technical grade, 90%
Synonym(s):
6-Mercaptonicotinic acid
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About This Item
Empirical Formula (Hill Notation):
C6H5NO2S
CAS Number:
Molecular Weight:
155.17
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
90%
Form:
solid
InChI
1S/C6H5NO2S/c8-6(9)4-1-2-5(10)7-3-4/h1-3H,(H,7,10)(H,8,9)
SMILES string
OC(=O)c1ccc(S)nc1
InChI key
JWWGTYCXARQFOT-UHFFFAOYSA-N
grade
technical grade
assay
90%
form
solid
mp
260-262 °C (dec.) (lit.)
functional group
carboxylic acid
Quality Level
Related Categories
Application
6-Mercaptopyridine-3-carboxylic acid may be used in the following processes:
- Fabrication of nanowell based sensors for the detection of improvised explosive devices (IEDs).
- Functionalization of gold nanoparticles (AuNPs) for the highly sensitive and selective detection of Cd2+ in colorimetric assay.
- Preparation of thiolated chitosans, which are thiolated biopolymers exhibiting mucoadhesive, enzyme inhibitory, and permeation enhancing properties.
- Synthesis of Zinc(II) coordination polymers.
General description
6-Mercaptopyridine-3-carboxylic acid (MPCA, 6-mercaptonicotinic acid, MNA) is a bifunctional ligand, made up of pyridine moiety containing carboxylic and mercapto group. The electrochemical properties of self-assembled monolayers (SAMs) of MNA on gold electrode have been described.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Gioconda Millotti et al.
Biomacromolecules, 10(11), 3023-3027 (2009-10-14)
Thiolated chitosans are relatively new thiolated biopolymers exhibiting mucoadhesive, enzyme inhibitory, and permeation enhancing properties. A drawback, however, is their pH dependent reactivity. The aim of this study was therefore to develop a novel thiolated chitosan showing a non pH
Ying Xue et al.
The Analyst, 136(18), 3725-3730 (2011-08-02)
We have developed a colorimetric assay for the highly sensitive and selective detection of Cd(2+) using gold nanoparticles (AuNPs) cofunctionalized with 6-mercaptonicotinic acid (MNA) and L-Cysteine (L-Cys) through the formation of an Au-S bond. In the presence of Cd(2+), the
Pei She et al.
Analytica chimica acta, 906, 139-147 (2016-01-17)
An immunochromatographic test (ICT) strip was developed for ultrasensitive competitive immunoassay of Hg(2+). This strategy was achieved by combining the easy-operation and rapidity of ICT with the high sensitivity of surface-enhanced Raman scattering (SERS). Monoclonal antibody (mAb) against Hg(2+) and
Highly sensitive and specific determination of mercury (II) ion in water, food and cosmetic samples with an ELISA based on a novel monoclonal antibody.
Wang Y, et al.
Analytical and Bioanalytical Chemistry, 403(9), 2519-2528 (2012)
A novel two-dimensional zinc (II) coordination polymer with 6-mercaptonicotinic acid.
Wang Y, et al.
Acta Crystallographica Section C, Crystal Structure Communications, 64(1), 70-72 (2008)
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