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Merck
CN

413143

Sigma-Aldrich

2,2′-Methylenebis(6-tert-butyl-4-ethylphenol)

Synonym(s):

2,2′-Methylenebis[6-(1,1-dimethylethyl)-4-ethylphenol], 2,2-Methylenebis(4-ethyl-6-tert -butylphenol), Bis(3-tert -butyl-5-ethyl-2-hydroxyphenyl)methane

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About This Item

Linear Formula:
CH2[C6H2[C(CH3)3](C2H5)OH]2
CAS Number:
Molecular Weight:
368.55
EC Number:
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23
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form

powder

Quality Level

mp

119-122 °C (lit.)

SMILES string

CCc1cc(Cc2cc(CC)cc(c2O)C(C)(C)C)c(O)c(c1)C(C)(C)C

InChI

1S/C25H36O2/c1-9-16-11-18(22(26)20(13-16)24(3,4)5)15-19-12-17(10-2)14-21(23(19)27)25(6,7)8/h11-14,26-27H,9-10,15H2,1-8H3

InChI key

GPNYZBKIGXGYNU-UHFFFAOYSA-N

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Application

Antioxidant

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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[Distribution of 2,2'-methylenebis (4-ethyl-6-tert-butylphenol) in rat tissues].
A Takagi et al.
Eisei Shikenjo hokoku. Bulletin of National Institute of Hygienic Sciences, (105)(105), 26-28 (1987-01-01)
[Distribution of 2,2'-methylenebis (4-ethyl-6-tert-butylphenol) in rat fat].
A Takagi
Eisei Shikenjo hokoku. Bulletin of National Institute of Hygienic Sciences, (106)(106), 105-106 (1988-01-01)
A Takagi et al.
The Journal of toxicological sciences, 18(1), 49-55 (1993-02-01)
Effects of 2,2'-methylenebis (4-ethyl-6-tert-butylphenol) (MBEBP) on hepatic mitochondrial oxidative phosphorylation in vitro, and on hepatic peroxisomal enzymes activities and microsomal mixed-function oxidase activities were studied. 1. A low concentration of MBEBP, less than 50 microM, increased state 4 respiration and
S Tanaka et al.
Eisei Shikenjo hokoku. Bulletin of National Institute of Hygienic Sciences, (107)(107), 51-55 (1989-01-01)
2,2'-Methylenebis (4-ethyl-6-tert-buthylphenol), an antioxidant, was given orally to pregnant Wistar rats by stomach intubation at the dose levels of 187, 375 or 750 mg/kg body weight during days 7 to 17 of gestation, and the effects of the compound on
A Takagi et al.
The Journal of toxicological sciences, 17(3), 135-153 (1992-08-01)
The acute and subchronic toxicity studies on 2,2'-methylenebis (4-ethyl-6-tert-butylphenol) (MBEBP) were conducted using male and female Wistar rats. In acute toxicity test, the LD50 values were estimated to be greater than 10 g/kg BW by oral and intraperitoneal administration in

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