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415464

N-Vinylcaprolactam

Name: <I>N</I>-Vinylcaprolactam
Brand: ALDRICH

98%, stabilized

Synonym(s):

1-Ethenylazepan-2-one, 1-Ethenylhexahydro-2H -azepin-2-one, 1-Vinylazepan-2-one

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About This Item

Empirical Formula (Hill Notation):

C₈H₁₃NO

CAS Number:

2235-00-9

Molecular Weight:

139.19

NACRES:

NA.23

PubChem Substance ID:

24866004

UNSPSC Code:

12162002

EC Number:

218-787-6

MDL number:

MFCD00080693

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Properties

Quality Level

100

assay

98%

form

solid

contains

~20 ppm HO-TEMPO as stabilizer

bp

128 °C/21 mmHg (lit.)

mp

35-38 °C (dec.) (lit.)

density

1.029 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

C=CN1CCCCCC1=O

InChI

1S/C8H13NO/c1-2-9-7-5-3-4-6-8(9)10/h2H,1,3-7H2

InChI key

JWYVGKFDLWWQJX-UHFFFAOYSA-N

Description

General description

N-Vinylcaprolactam (NVCL) is an organo-soluble amphiphilic material that is soluble in solvents like benzene, isobutanol, and isopropanol. It can be used in the preparation of poly(NVCL) by free-radical polymerization at a temperature higher than its melting point.

Application

NVCL forms a temperature responsive polymer, which can be used for a variety of biomedical applications.

pictograms

GHS08,GHS07

signalword

Danger

hcodes

H302 + H312,H317,H319,H372

pcodes

P260 - P280 - P301 + P312 - P302 + P352 + P312 - P305 + P351 + P338 - P314

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Sens. 1 - STOT RE 1

target_organs

Liver,Upper respiratory tract

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 1

flash_point_f

213.8 °F - closed cup

flash_point_c

101 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Synthesis, characterisation and phase transition behaviour of temperature-responsive physically crosslinked poly (N-vinylcaprolactam) based polymers for biomedical applications.

Shane C Halligan et al.

Materials science & engineering. C, Materials for biological applications, 79, 130-139 (2017-06-21)

Poly (N-vinylcaprolactam) (PNVCL) is a polymer which offers superior characteristics for various potential medical device applications. In particular it offers unique thermoresponsive capabilities, which fulfils the material technology constraints required in targeted drug delivery applications. PNVCL phase transitions can be

Two-step volume phase transition mechanism of poly(N-vinylcaprolactam) hydrogel online-tracked by two-dimensional correlation spectroscopy.

Gehong Su et al.

Physical chemistry chemical physics : PCCP, 19(40), 27221-27232 (2017-10-05)

In this study, temperature-dependent FTIR spectroscopy in combination with the perturbation-correlation moving-window (PCMW2D) technique and generalized two-dimensional (2D) correlation analysis was applied to investigate the phase transition mechanism of poly(N-vinylcaprolactam) (PVCL) hydrogel upon heating. In the conventional 1D FTIR spectra

Poly (N-vinylcaprolactam), a comprehensive review on a thermoresponsive polymer becoming popular

Cortez-Lemus NA and Licea-Claverie A

Progress in Polymer Science, 53(5), 1-51 (2016)

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Global Trade Item Number

SKU	GTIN
415464-500G	04061832089157
415464-100G	04061832089140