Skip to Content
Merck
CN

416762

5-Bromo-2,4-dichloropyrimidine

97%

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C4HBrCl2N2
CAS Number:
36082-50-5
Molecular Weight:
227.87
NACRES:
NA.22
PubChem Substance ID:
24865926
UNSPSC Code:
12352100
MDL number:
MFCD00127818
Assay:
97%
Form:
solid

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

5-Bromo-2,4-dichloropyrimidine, 97%

InChI

1S/C4HBrCl2N2/c5-2-1-8-4(7)9-3(2)6/h1H

SMILES string

Clc1ncc(Br)c(Cl)n1

InChI key

SIKXIUWKPGWBBF-UHFFFAOYSA-N

assay

97%

form

solid

refractive index

n20/D 1.603 (lit.)

bp

128 °C/15 mmHg (lit.)

mp

29-30 °C (lit.)

density

1.781 g/mL at 25 °C (lit.)

functional group

bromo
chloro

Quality Level

100

Related Categories

Application

5-Bromo-2,4-dichloropyrimidine may be employed as starting reagent for the synthesis of positive allosteric modulators for GABAB receptors (drug-like class of compounds) and pyridinepyrimidine analogs.

General description

5-Bromo-2,4-dichloropyrimidine is a halogenoprimidine. It has been reported as an intermediate during the synthesis of 2,4-di-t-butoxy-5-bromopyrimidine and 2,4-di-t-butoxy-5-pyrimidineboronic acid.

pictograms

Skull and crossbonesCorrosion
GHS06,GHS05

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges, type P3 (EN 143) respirator cartridges

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKCZ3152
MKCJ8291
MKBT7810V
MKBT0812V
MKBQ0397V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Sébastien Guery et al.
Bioorganic & medicinal chemistry letters, 17(22), 6206-6211 (2007-09-22)
The optimization of GS39783 into potent, selective, and safe positive allosteric modulators of GABA(B) receptors is presented.
Synthesis of Various 5-Substituted Uracils.
Peters D, et al.
Journal of Heterocyclic Chemistry, 27(7), 2165-2170 (1990)
Pyrimidines. Part VIII. Halogeno-and hydrazino-pyrimidines.
Chesterfield J, et al.
Journal of the Chemical Society, 3478-3481 (1955)
Synthesis, 5, 728-734 (2003)
Synthesis, 861-861 (2006)
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service