420107
Bromotris(dimethylamino)phosphonium hexafluorophosphate
98%
Synonym(s):
BroP, Bromotris(N-methylmethanaminato)-phosphorus hexafluorophosphate
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About This Item
Linear Formula:
BrP[N(CH3)2]3PF6
CAS Number:
Molecular Weight:
388.07
UNSPSC Code:
12352101
PubChem Substance ID:
MDL number:
assay
98%
reaction suitability
reaction type: Coupling Reactions
mp
>300 °C (lit.)
application(s)
peptide synthesis
SMILES string
F[P-](F)(F)(F)(F)F.CN(C)[P+](Br)(N(C)C)N(C)C
InChI
1S/C6H18BrN3P.F6P/c1-8(2)11(7,9(3)4)10(5)6;1-7(2,3,4,5)6/h1-6H3;/q+1;-1
InChI key
XELPBWPBGHCIKX-UHFFFAOYSA-N
Application
Reagent for:
Conjugate addition of nitroalkanes to an acrylate equivalent
A novel polymer supported approach to nucleoside modification
Asymmetric hydrogenations
Peptide coupling
Pyrrolidine hydroxylation
Synthesis of cyclic PNA-based compound directed against HIV-1 TAR RNA
Conjugate addition of nitroalkanes to an acrylate equivalent
A novel polymer supported approach to nucleoside modification
Asymmetric hydrogenations
Peptide coupling
Pyrrolidine hydroxylation
Synthesis of cyclic PNA-based compound directed against HIV-1 TAR RNA
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
wgk
WGK 3
signalword
Danger
hcodes
Hazard Classifications
Carc. 1B - Skin Corr. 1B
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Regulatory Information
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S C Posey et al.
The Journal of biological chemistry, 274(7), 4259-4265 (1999-02-06)
Participation of the actin cytoskeleton in the transduction of proliferative signals has been established through the use of compounds that disrupt the cytoskeleton. To address the possibility that actin also participates in the transduction of an apoptotic signal, we have
V R Scott et al.
Antimicrobial agents and chemotherapy, 32(8), 1154-1157 (1988-08-01)
Jasplakinolide is a cyclodepsipeptide which represents a new class of antifungal agents with potent activity against Candida albicans. Jasplakinolide is fungicidal against C. albicans with both a MIC and a minimum lethal concentration of 25 micrograms/ml in a broth dilution
M R Bubb et al.
The Journal of biological chemistry, 269(21), 14869-14871 (1994-05-27)
Jasplakinolide, a naturally occurring cyclic peptide from the marine sponge, Jaspis johnstoni, has both fungicidal and antiproliferative activity. We now report that this peptide is a potent inducer of actin polymerization in vitro. The peptide has a much greater effect
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 420107-250MG | 04061833280027 |