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420247

(+)-Borneol

Name: (+)-Borneol
Brand: ALDRICH

97%

Synonym(s):

endo-(1R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol

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About This Item

Empirical Formula (Hill Notation):

C₁₀H₁₈O

CAS Number:

464-43-7

Molecular Weight:

154.25

UNSPSC Code:

12352212

NACRES:

NA.22

PubChem Substance ID:

24866321

EC Number:

207-352-6

Beilstein/REAXYS Number:

2038056

MDL number:

MFCD00066427

Assay:

97%

Form:

solid

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Properties

Quality Level

200

assay

97%

form

solid

optical activity

[α]20/D +36°, c = 5 in ethanol

mp

206-209 °C (lit.)

functional group

hydroxyl

SMILES string

[H][C@@]12CC[C@@](C)([C@@H](O)C1)C2(C)C

InChI

1S/C10H18O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7-8,11H,4-6H2,1-3H3/t7-,8+,10+/m1/s1

InChI key

DTGKSKDOIYIVQL-WEDXCCLWSA-N

Gene Information

human ... UGT1A4(54657)

Description

General description

(+)-Borneol, a bicyclic monoterpene, is found in the essential oils of medicinal plants and is commonly used in traditional Chinese medicine for analgesia and anaesthesia.

Application

(+)-Borneol has been used to study its antiapoptotic, antioxidative and neuroprotective effect in human neuroblastoma cells (SH-SY5Y).

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

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pictograms

GHS02

signalword

Warning

hcodes

H228

pcodes

P210 - P240 - P241 - P280 - P370 + P378

Hazard Classifications

Flam. Sol. 2

Storage Class

4.1B - Flammable solid hazardous materials

wgk

WGK 3

flash_point_f

149.0 °F - closed cup

flash_point_c

65 °C - closed cup

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

Regulatory Information

危险化学品

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Certificates of Analysis (COA)

Lot/Batch Number

0000506330

0000479716

0000204322

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Borneol alleviates oxidative stress via upregulation of Nrf2 and Bcl-2 in SH-SY5Y cells.

Hur J, et al.

Pharmaceutical Analysis, 51(1), 30-35 (2013)

(+)-And (-)-borneol: efficacious positive modulators of GABA action at human recombinant a 1 ? 2 ? 2L GABA A receptors.

Granger RE, et al.

Biochemical Pharmacology, 69(7), 1101-1111 (2005)

Comparative pharmacokinetic studies of borneol in mouse plasma and brain by different administrations.

Jing-yi Zhao et al.

Journal of Zhejiang University. Science. B, 13(12), 990-996 (2012-12-12)

Borneol, a monoterpenoid alcohol, is used widely, particularly in combined formulas for preventing and curing cardiovascular and cerebrovascular diseases in traditional Chinese medicine. In order to understand the blood and brain pharmacokinetics after intravenous, intranasal, or oral administration and to

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Global Trade Item Number

SKU	GTIN
420247-1G	04061832092942