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Merck
CN

43200

trans-1,3-Diphenyl-2-propen-1-ol

≥98.0% (HPLC)

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About This Item

Empirical Formula (Hill Notation):
C15H14O
CAS Number:
Molecular Weight:
210.27
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1951697
Assay:
≥98.0% (HPLC)
Form:
solid
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InChI

1S/C15H14O/c16-15(14-9-5-2-6-10-14)12-11-13-7-3-1-4-8-13/h1-12,15-16H/b12-11+

SMILES string

OC(\C=C\c1ccccc1)c2ccccc2

InChI key

ORACYDGVNJGDMI-VAWYXSNFSA-N

assay

≥98.0% (HPLC)

form

solid

mp

55-57 °C

functional group

hydroxyl, phenyl

storage temp.

2-8°C

Quality Level

General description

trans-1,3-diphenyl-2-propen-1-ol is an allylic alcohol. It has been reported to exhibit significant in vivo anti-inflammatory activity. Allylic amination of trans-1,3-diphenyl-2-propen-1-ol catalyzed by water-soluble calix[4]resorcinarene sulfonic acid has been reported.

Application

trans-1,3-diphenyl-2-propen-1-ol may be used as a model substrate to investigate the formation of substituted cyclopropanes by SiO2-ZrO2 mixed oxides catalyzed Friedel-Crafts-alkylation followed by trans-hydrogenation.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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High-Surface-Area SiO2-ZrO2 Mixed Oxides as Catalysts for the Friedel-Crafts-Type Alkylation of Arenes with Alcohols and Tandem Cyclopropanation Reactions.
Kaper H, et al.
ChemCatChem, 4(11), 1813-1818 (2012)
Direct Nucleophilic SN1-Type Reactions of Alcohols.
Emer E, et al.
European Journal of Organic Chemistry, 4, 647-666 (2011)
Molecular topology as a novel approach for drug discovery.
Galvez J, et al.
Expert Opinion on Drug Delivery, 7(2), 133-153 (2012)
Xinqin Liu et al.
International journal of biological sciences, 13(11), 1351-1360 (2017-12-07)
Lead (Pb) is a well-known neurotoxicant and a risk factor for neurologic disorders. The blood brain barrier (BBB) plays an important role in the maintenance of optimal brain function. BBB is a target of Pb, and studies have shown that

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